4pdc
From Proteopedia
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==Crystal structure of Cowpox virus CPXV018 (OMCP) bound to human NKG2D== | ==Crystal structure of Cowpox virus CPXV018 (OMCP) bound to human NKG2D== | ||
| - | <StructureSection load='4pdc' size='340' side='right' caption='[[4pdc]], [[Resolution|resolution]] 1.99Å' scene=''> | + | <StructureSection load='4pdc' size='340' side='right'caption='[[4pdc]], [[Resolution|resolution]] 1.99Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4pdc]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PDC OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4pdc]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Cowpox_virus Cowpox virus] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PDC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PDC FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.991Å</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pdc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pdc OCA], [https://pdbe.org/4pdc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pdc RCSB], [https://www.ebi.ac.uk/pdbsum/4pdc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pdc ProSAT]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/NKG2D_HUMAN NKG2D_HUMAN] Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes. | ||
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| + | ==See Also== | ||
| + | *[[NK cell receptor|NK cell receptor]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Cowpox virus]] |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Fremont DH]] |
| - | [[Category: | + | [[Category: Lazear E]] |
| - | [[Category: | + | [[Category: Nelson CA]] |
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Current revision
Crystal structure of Cowpox virus CPXV018 (OMCP) bound to human NKG2D
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