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3leg

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==Lectin Domain of Lectinolysin complexed with Lewis Y Antigen==
==Lectin Domain of Lectinolysin complexed with Lewis Y Antigen==
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<StructureSection load='3leg' size='340' side='right' caption='[[3leg]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
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<StructureSection load='3leg' size='340' side='right'caption='[[3leg]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3leg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_mitis Streptococcus mitis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LEG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LEG FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3leg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_mitis Streptococcus mitis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LEG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LEG FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BDZ:6-DEOXY-ALPHA-L-GALACTOPYRANOSYL-(1- 3)-[6-DEOXY-ALPHA-L-GALACTOPYRANOSYL-(1- 2)-BETA-D-GALACTOPYRANOSYL-(1- 4)]-2-(ACETYLAMINO)-2-DEOXY-BETA-D-GLUCOPYRANOSE'>BDZ</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.01&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3leo|3leo]], [[3lei|3lei]], [[3lek|3lek]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=PRD_900054:Lewis+Y+antigen,+beta+anomer'>PRD_900054</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">samhpaf ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=28037 Streptococcus mitis])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3leg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3leg OCA], [https://pdbe.org/3leg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3leg RCSB], [https://www.ebi.ac.uk/pdbsum/3leg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3leg ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3leg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3leg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3leg RCSB], [http://www.ebi.ac.uk/pdbsum/3leg PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q2PHL4_STRMT Q2PHL4_STRMT]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Structure of the lectin regulatory domain of the cholesterol-dependent cytolysin lectinolysin reveals the basis for its lewis antigen specificity.,Feil SC, Lawrence S, Mulhern TD, Holien JK, Hotze EM, Farrand S, Tweten RK, Parker MW Structure. 2012 Feb 8;20(2):248-58. PMID:22325774<ref>PMID:22325774</ref>
Structure of the lectin regulatory domain of the cholesterol-dependent cytolysin lectinolysin reveals the basis for its lewis antigen specificity.,Feil SC, Lawrence S, Mulhern TD, Holien JK, Hotze EM, Farrand S, Tweten RK, Parker MW Structure. 2012 Feb 8;20(2):248-58. PMID:22325774<ref>PMID:22325774</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3leg" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Streptococcus mitis]]
[[Category: Streptococcus mitis]]
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[[Category: Feil, S C.]]
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[[Category: Feil SC]]
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[[Category: Blood clotting]]
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[[Category: Lectin domain of lectinolysin]]
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[[Category: Lewis y antigen]]
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[[Category: Nickel]]
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Current revision

Lectin Domain of Lectinolysin complexed with Lewis Y Antigen

PDB ID 3leg

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