3cjj

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==Crystal structure of human rage ligand-binding domain==
==Crystal structure of human rage ligand-binding domain==
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<StructureSection load='3cjj' size='340' side='right' caption='[[3cjj]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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<StructureSection load='3cjj' size='340' side='right'caption='[[3cjj]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3cjj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CJJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CJJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3cjj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CJJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CJJ FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AGER, RAGE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cjj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cjj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3cjj RCSB], [http://www.ebi.ac.uk/pdbsum/3cjj PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cjj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cjj OCA], [https://pdbe.org/3cjj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cjj RCSB], [https://www.ebi.ac.uk/pdbsum/3cjj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cjj ProSAT]</span></td></tr>
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<table>
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</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cj/3cjj_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cj/3cjj_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cjj ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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Structural basis for ligand recognition and activation of RAGE.,Koch M, Chitayat S, Dattilo BM, Schiefner A, Diez J, Chazin WJ, Fritz G Structure. 2010 Oct 13;18(10):1342-52. PMID:20947022<ref>PMID:20947022</ref>
Structural basis for ligand recognition and activation of RAGE.,Koch M, Chitayat S, Dattilo BM, Schiefner A, Diez J, Chazin WJ, Fritz G Structure. 2010 Oct 13;18(10):1342-52. PMID:20947022<ref>PMID:20947022</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3cjj" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Chazin, W J.]]
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[[Category: Large Structures]]
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[[Category: Dattilo, B M.]]
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[[Category: Chazin WJ]]
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[[Category: Diez, J.]]
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[[Category: Dattilo BM]]
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[[Category: Fritz, G.]]
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[[Category: Diez J]]
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[[Category: Koch, M.]]
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[[Category: Fritz G]]
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[[Category: Schiefner, A.]]
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[[Category: Koch M]]
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[[Category: Glycoprotein]]
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[[Category: Schiefner A]]
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[[Category: Immunoglobulin domain]]
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[[Category: Membrane]]
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[[Category: Membrane protein]]
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[[Category: Secreted]]
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[[Category: Signaling protein]]
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[[Category: Transmembrane]]
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Current revision

Crystal structure of human rage ligand-binding domain

PDB ID 3cjj

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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