4nfb

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==Structure of paired immunoglobulin-like type 2 receptor (PILR )==
==Structure of paired immunoglobulin-like type 2 receptor (PILR )==
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<StructureSection load='4nfb' size='340' side='right' caption='[[4nfb]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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<StructureSection load='4nfb' size='340' side='right'caption='[[4nfb]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4nfb]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NFB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NFB FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4nfb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NFB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NFB FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1qfo|1qfo]], [[1o7v|1o7v]], [[2zg2|2zg2]], [[4nfd|4nfd]], [[4nfc|4nfc]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nfb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nfb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nfb RCSB], [http://www.ebi.ac.uk/pdbsum/4nfb PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nfb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nfb OCA], [https://pdbe.org/4nfb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nfb RCSB], [https://www.ebi.ac.uk/pdbsum/4nfb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nfb ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PILRA_HUMAN PILRA_HUMAN] Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRA is thought to act as a cellular signaling inhibitory receptor by recruiting cytoplasmic phosphatases like PTPN6/SHP-1 and PTPN11/SHP-2 via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules. Receptor for PIANP.<ref>PMID:10903717</ref> <ref>PMID:18358807</ref> <ref>PMID:21241660</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Fan, Z.]]
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[[Category: Homo sapiens]]
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[[Category: Gao, G.]]
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[[Category: Large Structures]]
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[[Category: Li, Y.]]
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[[Category: Fan Z]]
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[[Category: Lu, G.]]
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[[Category: Gao G]]
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[[Category: Lu, Q.]]
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[[Category: Li Y]]
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[[Category: Qi, J.]]
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[[Category: Lu G]]
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[[Category: Wang, H.]]
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[[Category: Lu Q]]
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[[Category: Yan, J.]]
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[[Category: Qi J]]
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[[Category: Zhang, Y.]]
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[[Category: Wang H]]
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[[Category: Cell surface]]
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[[Category: Yan J]]
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[[Category: Hsv-1 gb]]
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[[Category: Zhang Y]]
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[[Category: Igv-like]]
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[[Category: Immune system]]
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[[Category: Immune-related inhibition receptor]]
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Current revision

Structure of paired immunoglobulin-like type 2 receptor (PILR )

PDB ID 4nfb

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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