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4nfb
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==Structure of paired immunoglobulin-like type 2 receptor (PILR )== | ==Structure of paired immunoglobulin-like type 2 receptor (PILR )== | ||
| - | <StructureSection load='4nfb' size='340' side='right' caption='[[4nfb]], [[Resolution|resolution]] 1.60Å' scene=''> | + | <StructureSection load='4nfb' size='340' side='right'caption='[[4nfb]], [[Resolution|resolution]] 1.60Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4nfb]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NFB OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4nfb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NFB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NFB FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nfb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nfb OCA], [https://pdbe.org/4nfb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nfb RCSB], [https://www.ebi.ac.uk/pdbsum/4nfb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nfb ProSAT]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PILRA_HUMAN PILRA_HUMAN] Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRA is thought to act as a cellular signaling inhibitory receptor by recruiting cytoplasmic phosphatases like PTPN6/SHP-1 and PTPN11/SHP-2 via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules. Receptor for PIANP.<ref>PMID:10903717</ref> <ref>PMID:18358807</ref> <ref>PMID:21241660</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Fan | + | [[Category: Homo sapiens]] |
| - | [[Category: Gao | + | [[Category: Large Structures]] |
| - | [[Category: Li | + | [[Category: Fan Z]] |
| - | [[Category: Lu | + | [[Category: Gao G]] |
| - | [[Category: Lu | + | [[Category: Li Y]] |
| - | [[Category: Qi | + | [[Category: Lu G]] |
| - | [[Category: Wang | + | [[Category: Lu Q]] |
| - | [[Category: Yan | + | [[Category: Qi J]] |
| - | [[Category: Zhang | + | [[Category: Wang H]] |
| - | + | [[Category: Yan J]] | |
| - | + | [[Category: Zhang Y]] | |
| - | + | ||
| - | + | ||
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Current revision
Structure of paired immunoglobulin-like type 2 receptor (PILR )
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Categories: Homo sapiens | Large Structures | Fan Z | Gao G | Li Y | Lu G | Lu Q | Qi J | Wang H | Yan J | Zhang Y
