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3ow1

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==Crystal structure of D-mannonate dehydratase from Chromohalobacter salexigens complexed with MG==
==Crystal structure of D-mannonate dehydratase from Chromohalobacter salexigens complexed with MG==
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<StructureSection load='3ow1' size='340' side='right' caption='[[3ow1]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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<StructureSection load='3ow1' size='340' side='right'caption='[[3ow1]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ow1]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Chromohalobacter_salexigens Chromohalobacter salexigens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OW1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OW1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ow1]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Chromohalobacter_salexigens Chromohalobacter salexigens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OW1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OW1 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.798&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3bsm|3bsm]], [[3p93|3p93]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Csal_2974 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158080 Chromohalobacter salexigens])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ow1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ow1 OCA], [https://pdbe.org/3ow1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ow1 RCSB], [https://www.ebi.ac.uk/pdbsum/3ow1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ow1 ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ow1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ow1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ow1 RCSB], [http://www.ebi.ac.uk/pdbsum/3ow1 PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/DMGD_CHRSD DMGD_CHRSD] Has low dehydratase activity with D-mannonate and D-gluconate, suggesting that these are not physiological substrates and that it has no significant role in the in vivo degradation of these compounds. Has no detectable activity with a panel of 70 other acid sugars (in vitro).<ref>PMID:24697546</ref>
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==See Also==
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*[[Mandelate racemase/muconate lactonizing enzyme 3D structures|Mandelate racemase/muconate lactonizing enzyme 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Chromohalobacter salexigens]]
[[Category: Chromohalobacter salexigens]]
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[[Category: Almo, S C.]]
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[[Category: Large Structures]]
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[[Category: Fedorov, A A.]]
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[[Category: Almo SC]]
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[[Category: Fedorov, E V.]]
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[[Category: Fedorov AA]]
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[[Category: Gerlt, J A.]]
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[[Category: Fedorov EV]]
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[[Category: Wichelecki, D.]]
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[[Category: Gerlt JA]]
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[[Category: D-mannonate dehydratase]]
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[[Category: Wichelecki D]]
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[[Category: Lyase]]
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Current revision

Crystal structure of D-mannonate dehydratase from Chromohalobacter salexigens complexed with MG

PDB ID 3ow1

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