3p0v
From Proteopedia
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==anti-EGFR/HER3 Fab DL11 alone== | ==anti-EGFR/HER3 Fab DL11 alone== | ||
| - | <StructureSection load='3p0v' size='340' side='right' caption='[[3p0v]], [[Resolution|resolution]] 2.85Å' scene=''> | + | <StructureSection load='3p0v' size='340' side='right'caption='[[3p0v]], [[Resolution|resolution]] 2.85Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3p0v]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3p0v]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P0V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P0V FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85Å</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p0v OCA], [https://pdbe.org/3p0v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p0v RCSB], [https://www.ebi.ac.uk/pdbsum/3p0v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p0v ProSAT]</span></td></tr> |
| - | <table> | + | </table> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies.,Schaefer G, Haber L, Crocker LM, Shia S, Shao L, Dowbenko D, Totpal K, Wong A, Lee CV, Stawicki S, Clark R, Fields C, Lewis Phillips GD, Prell RA, Danilenko DM, Franke Y, Stephan JP, Hwang J, Wu Y, Bostrom J, Sliwkowski MX, Fuh G, Eigenbrot C Cancer Cell. 2011 Oct 18;20(4):472-86. PMID:22014573<ref>PMID:22014573</ref> | A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies.,Schaefer G, Haber L, Crocker LM, Shia S, Shao L, Dowbenko D, Totpal K, Wong A, Lee CV, Stawicki S, Clark R, Fields C, Lewis Phillips GD, Prell RA, Danilenko DM, Franke Y, Stephan JP, Hwang J, Wu Y, Bostrom J, Sliwkowski MX, Fuh G, Eigenbrot C Cancer Cell. 2011 Oct 18;20(4):472-86. PMID:22014573<ref>PMID:22014573</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
| + | <div class="pdbe-citations 3p0v" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Eigenbrot C]] |
| - | [[Category: | + | [[Category: Shia S]] |
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Current revision
anti-EGFR/HER3 Fab DL11 alone
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