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3oss

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==The crystal structure of enterotoxigenic Escherichia coli GspC-GspD complex from the type II secretion system==
==The crystal structure of enterotoxigenic Escherichia coli GspC-GspD complex from the type II secretion system==
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<StructureSection load='3oss' size='340' side='right' caption='[[3oss]], [[Resolution|resolution]] 2.63&Aring;' scene=''>
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<StructureSection load='3oss' size='340' side='right'caption='[[3oss]], [[Resolution|resolution]] 2.63&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3oss]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OSS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OSS FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3oss]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_ETEC_H10407 Escherichia coli ETEC H10407]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OSS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OSS FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.63&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GSPC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli]), GSPD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3oss FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3oss OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3oss RCSB], [http://www.ebi.ac.uk/pdbsum/3oss PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3oss FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3oss OCA], [https://pdbe.org/3oss PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3oss RCSB], [https://www.ebi.ac.uk/pdbsum/3oss PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3oss ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GSPD2_ECOH1 GSPD2_ECOH1] Part of a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of folded proteins across the outer membrane (Probable). This subunit forms the outer membrane channel (Probable).<ref>PMID:22585966</ref> <ref>PMID:23820381</ref> <ref>PMID:29632366</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Structural and functional studies on the interaction of GspC and GspD in the type II secretion system.,Korotkov KV, Johnson TL, Jobling MG, Pruneda J, Pardon E, Heroux A, Turley S, Steyaert J, Holmes RK, Sandkvist M, Hol WG PLoS Pathog. 2011 Sep;7(9):e1002228. Epub 2011 Sep 8. PMID:21931548<ref>PMID:21931548</ref>
Structural and functional studies on the interaction of GspC and GspD in the type II secretion system.,Korotkov KV, Johnson TL, Jobling MG, Pruneda J, Pardon E, Heroux A, Turley S, Steyaert J, Holmes RK, Sandkvist M, Hol WG PLoS Pathog. 2011 Sep;7(9):e1002228. Epub 2011 Sep 8. PMID:21931548<ref>PMID:21931548</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3oss" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Escherichia coli]]
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[[Category: Escherichia coli ETEC H10407]]
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[[Category: Hol, W G.J.]]
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[[Category: Large Structures]]
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[[Category: Korotkov, K V.]]
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[[Category: Hol WGJ]]
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[[Category: Pruneda, J.]]
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[[Category: Korotkov KV]]
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[[Category: General secretory pathway]]
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[[Category: Pruneda J]]
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[[Category: Hr domain]]
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[[Category: Lanthanide-binding tag]]
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[[Category: Protein transport]]
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[[Category: Secretin]]
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Current revision

The crystal structure of enterotoxigenic Escherichia coli GspC-GspD complex from the type II secretion system

PDB ID 3oss

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