3np6

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==The crystal structure of Berberine bound to DNA d(CGTACG)==
==The crystal structure of Berberine bound to DNA d(CGTACG)==
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<StructureSection load='3np6' size='340' side='right' caption='[[3np6]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='3np6' size='340' side='right'caption='[[3np6]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3np6]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NP6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NP6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3np6]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NP6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NP6 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BER:BERBERINE'>BER</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3nx5|3nx5]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BER:BERBERINE'>BER</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3np6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3np6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3np6 RCSB], [http://www.ebi.ac.uk/pdbsum/3np6 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3np6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3np6 OCA], [https://pdbe.org/3np6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3np6 RCSB], [https://www.ebi.ac.uk/pdbsum/3np6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3np6 ProSAT]</span></td></tr>
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<table>
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</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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X-Ray diffraction analyses of the natural isoquinoline alkaloids Berberine and Sanguinarine complexed with double helix DNA d(CGTACG).,Ferraroni M, Bazzicalupi C, Bilia AR, Gratteri P Chem Commun (Camb). 2011 May 7;47(17):4917-9. Epub 2011 Mar 22. PMID:21431128<ref>PMID:21431128</ref>
X-Ray diffraction analyses of the natural isoquinoline alkaloids Berberine and Sanguinarine complexed with double helix DNA d(CGTACG).,Ferraroni M, Bazzicalupi C, Bilia AR, Gratteri P Chem Commun (Camb). 2011 May 7;47(17):4917-9. Epub 2011 Mar 22. PMID:21431128<ref>PMID:21431128</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3np6" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bazzicalupi, C.]]
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[[Category: Large Structures]]
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[[Category: Bilia, A R.]]
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[[Category: Bazzicalupi C]]
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[[Category: Ferraroni, M.]]
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[[Category: Bilia AR]]
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[[Category: Gratteri, P.]]
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[[Category: Ferraroni M]]
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[[Category: B-dna]]
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[[Category: Gratteri P]]
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[[Category: Dna]]
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[[Category: Double helix]]
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[[Category: Drug-dna complex]]
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Current revision

The crystal structure of Berberine bound to DNA d(CGTACG)

PDB ID 3np6

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