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4cbc

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==Open-form NavMS Sodium Channel Pore (with C-terminal Domain) after thallium soak==
==Open-form NavMS Sodium Channel Pore (with C-terminal Domain) after thallium soak==
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<StructureSection load='4cbc' size='340' side='right' caption='[[4cbc]], [[Resolution|resolution]] 2.66&Aring;' scene=''>
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<StructureSection load='4cbc' size='340' side='right'caption='[[4cbc]], [[Resolution|resolution]] 2.66&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4cbc]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CBC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CBC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4cbc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Magnetococcus_marinus_MC-1 Magnetococcus marinus MC-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CBC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CBC FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2CV:HEGA-10'>2CV</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.664&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cal|4cal]], [[4cbd|4cbd]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2CV:HEGA-10'>2CV</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cbc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cbc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cbc RCSB], [http://www.ebi.ac.uk/pdbsum/4cbc PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cbc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cbc OCA], [https://pdbe.org/4cbc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cbc RCSB], [https://www.ebi.ac.uk/pdbsum/4cbc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cbc ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0L5S6_MAGMM A0L5S6_MAGMM]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Prokaryotic NavMs channel as a structural and functional model for eukaryotic sodium channel antagonism.,Bagneris C, DeCaen PG, Naylor CE, Pryde DC, Nobeli I, Clapham DE, Wallace BA Proc Natl Acad Sci U S A. 2014 May 21. pii: 201406855. PMID:24850863<ref>PMID:24850863</ref>
Prokaryotic NavMs channel as a structural and functional model for eukaryotic sodium channel antagonism.,Bagneris C, DeCaen PG, Naylor CE, Pryde DC, Nobeli I, Clapham DE, Wallace BA Proc Natl Acad Sci U S A. 2014 May 21. pii: 201406855. PMID:24850863<ref>PMID:24850863</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4cbc" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Ion channels 3D structures|Ion channels 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bagneris, C.]]
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[[Category: Large Structures]]
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[[Category: Naylor, C E.]]
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[[Category: Magnetococcus marinus MC-1]]
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[[Category: Wallace, B A.]]
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[[Category: Bagneris C]]
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[[Category: Membrane protein]]
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[[Category: Naylor CE]]
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[[Category: Selectivity filter]]
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[[Category: Wallace BA]]
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[[Category: Sodium channel]]
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[[Category: Transport protein]]
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Current revision

Open-form NavMS Sodium Channel Pore (with C-terminal Domain) after thallium soak

PDB ID 4cbc

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