3pf4

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==Crystal structure of Bs-CspB in complex with r(GUCUUUA)==
==Crystal structure of Bs-CspB in complex with r(GUCUUUA)==
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<StructureSection load='3pf4' size='340' side='right' caption='[[3pf4]], [[Resolution|resolution]] 1.38&Aring;' scene=''>
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<StructureSection load='3pf4' size='340' side='right'caption='[[3pf4]], [[Resolution|resolution]] 1.38&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3pf4]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PF4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PF4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3pf4]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PF4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PF4 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.38&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1csp|1csp]], [[2hax|2hax]], [[2es2|2es2]], [[2f52|2f52]], [[1c9o|1c9o]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BSU09100, cspA, cspB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pf4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pf4 OCA], [https://pdbe.org/3pf4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pf4 RCSB], [https://www.ebi.ac.uk/pdbsum/3pf4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pf4 ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pf4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pf4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pf4 RCSB], [http://www.ebi.ac.uk/pdbsum/3pf4 PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/CSPB_BACSU CSPB_BACSU] Binds to the pentamer sequences ATTGG and CCAAT with highest affinity in single-stranded DNA, and also to other sequences. Has greater affinity for ATTGG than CCAAT. Can act as transcriptional activator of cold shock genes by recognizing putative ATTGG-box elements present in promoter regions of genes induced under cold shock conditions.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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RNA single strands bind to a conserved surface of the major cold shock protein in crystals and solution.,Sachs R, Max KE, Heinemann U, Balbach J RNA. 2011 Nov 29. PMID:22128343<ref>PMID:22128343</ref>
RNA single strands bind to a conserved surface of the major cold shock protein in crystals and solution.,Sachs R, Max KE, Heinemann U, Balbach J RNA. 2011 Nov 29. PMID:22128343<ref>PMID:22128343</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3pf4" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Heinemann, U.]]
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[[Category: Large Structures]]
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[[Category: Max, K E.A.]]
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[[Category: Heinemann U]]
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[[Category: Sachs, R.]]
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[[Category: Max KEA]]
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[[Category: Beta barrel]]
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[[Category: Sachs R]]
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[[Category: Cold shock domain]]
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[[Category: Cold shock response]]
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[[Category: Cytosol]]
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[[Category: Gene regulation-rna complex]]
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[[Category: Ob fold]]
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[[Category: Protein-rna complex]]
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[[Category: Rna/dna binding]]
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[[Category: Single-stranded rna and dna]]
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[[Category: Transcription regulation]]
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[[Category: Translation regulation]]
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Current revision

Crystal structure of Bs-CspB in complex with r(GUCUUUA)

PDB ID 3pf4

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