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3qdp

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==Structural characterization of the interaction of colicin A, colicin N, and TolB with TolAIII translocon==
==Structural characterization of the interaction of colicin A, colicin N, and TolB with TolAIII translocon==
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<StructureSection load='3qdp' size='340' side='right' caption='[[3qdp]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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<StructureSection load='3qdp' size='340' side='right'caption='[[3qdp]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3qdp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QDP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QDP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3qdp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QDP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QDP FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene>, <scene name='pdbligand=MLZ:N-METHYL-LYSINE'>MLZ</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene>, <scene name='pdbligand=MLZ:N-METHYL-LYSINE'>MLZ</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qdr|3qdr]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qdp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qdp OCA], [https://pdbe.org/3qdp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qdp RCSB], [https://www.ebi.ac.uk/pdbsum/3qdp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qdp ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tolA, cim, excC, lky, b0739, JW0729 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
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</table>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qdp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qdp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qdp RCSB], [http://www.ebi.ac.uk/pdbsum/3qdp PDBsum]</span></td></tr>
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== Function ==
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<table>
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[https://www.uniprot.org/uniprot/TOLA_ECOLI TOLA_ECOLI] Involved in the TonB-independent uptake of group A colicins (colicins A, E1, E2, E3, and K). Necessary for the colicins to reach their respective targets after initial binding to the bacteria. Also involved in the translocation of bacteriophage DNA.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Structural evidence that colicin A binds to a novel binding site of TolA in the E.coli periplasm.,Li C, Zhang Y, Vankemmelbeke M, Hecht O, Aleanizy FS, Macdonald C, Moore GR, James R, Penfold CN J Biol Chem. 2012 Apr 9. PMID:22493500<ref>PMID:22493500</ref>
Structural evidence that colicin A binds to a novel binding site of TolA in the E.coli periplasm.,Li C, Zhang Y, Vankemmelbeke M, Hecht O, Aleanizy FS, Macdonald C, Moore GR, James R, Penfold CN J Biol Chem. 2012 Apr 9. PMID:22493500<ref>PMID:22493500</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3qdp" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Escherichia coli]]
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[[Category: Escherichia coli K-12]]
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[[Category: Li, C.]]
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[[Category: Large Structures]]
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[[Category: Cola]]
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[[Category: Li C]]
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[[Category: Colicin]]
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[[Category: Coln]]
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[[Category: Methylation]]
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[[Category: Protein transport]]
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[[Category: Tola]]
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[[Category: Tolb]]
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[[Category: Translocation]]
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Current revision

Structural characterization of the interaction of colicin A, colicin N, and TolB with TolAIII translocon

PDB ID 3qdp

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