3qr8

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==Crystal structure of the bacteriophage P2 membrane-piercing protein gpV==
==Crystal structure of the bacteriophage P2 membrane-piercing protein gpV==
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<StructureSection load='3qr8' size='340' side='right' caption='[[3qr8]], [[Resolution|resolution]] 2.03&Aring;' scene=''>
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<StructureSection load='3qr8' size='340' side='right'caption='[[3qr8]], [[Resolution|resolution]] 2.03&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3qr8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_p2 Enterobacteria phage p2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QR8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QR8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3qr8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_P2 Escherichia virus P2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QR8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QR8 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.03&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qr7|3qr7]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qr8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qr8 OCA], [https://pdbe.org/3qr8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qr8 RCSB], [https://www.ebi.ac.uk/pdbsum/3qr8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qr8 ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">V ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10679 Enterobacteria phage P2])</td></tr>
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</table>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qr8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qr8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qr8 RCSB], [http://www.ebi.ac.uk/pdbsum/3qr8 PDBsum]</span></td></tr>
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== Function ==
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<table>
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[https://www.uniprot.org/uniprot/SPIKE_BPP2 SPIKE_BPP2] Forms the small spikes on the baseplate that plug the end of the tube before DNA ejection and form a channel perforating the host membrane during ejection. Involved in baseplate assembly.<ref>PMID:21821878</ref> <ref>PMID:22325780</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Phage pierces the host cell membrane with the iron-loaded spike.,Browning C, Shneider MM, Bowman VD, Schwarzer D, Leiman PG Structure. 2012 Feb 8;20(2):326-39. PMID:22325780<ref>PMID:22325780</ref>
Phage pierces the host cell membrane with the iron-loaded spike.,Browning C, Shneider MM, Bowman VD, Schwarzer D, Leiman PG Structure. 2012 Feb 8;20(2):326-39. PMID:22325780<ref>PMID:22325780</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3qr8" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Enterobacteria phage p2]]
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[[Category: Escherichia virus P2]]
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[[Category: Browning, C.]]
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[[Category: Large Structures]]
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[[Category: Leiman, P G.]]
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[[Category: Browning C]]
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[[Category: Shneider, M.]]
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[[Category: Leiman PG]]
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[[Category: Beta-helix]]
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[[Category: Shneider M]]
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[[Category: Cell membrane piercing]]
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[[Category: Iron-binding]]
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[[Category: Ob-fold]]
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[[Category: Phage baseplate]]
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[[Category: Tail spike]]
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[[Category: Viral protein]]
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Current revision

Crystal structure of the bacteriophage P2 membrane-piercing protein gpV

PDB ID 3qr8

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