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3sms

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==Human Pantothenate kinase 3 in complex with a pantothenate analog==
==Human Pantothenate kinase 3 in complex with a pantothenate analog==
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<StructureSection load='3sms' size='340' side='right' caption='[[3sms]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='3sms' size='340' side='right'caption='[[3sms]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3sms]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SMS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SMS FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3sms]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SMS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SMS FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=RNH:(2R)-N-[3-(HEPTYLAMINO)-3-OXOPROPYL]-2,4-DIHYDROXY-3,3-DIMETHYLBUTANAMIDE'>RNH</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PANK3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=RNH:(2R)-N-[3-(HEPTYLAMINO)-3-OXOPROPYL]-2,4-DIHYDROXY-3,3-DIMETHYLBUTANAMIDE'>RNH</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pantothenate_kinase Pantothenate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.33 2.7.1.33] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sms FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sms OCA], [https://pdbe.org/3sms PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sms RCSB], [https://www.ebi.ac.uk/pdbsum/3sms PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sms ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sms FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sms OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3sms RCSB], [http://www.ebi.ac.uk/pdbsum/3sms PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/PANK3_HUMAN PANK3_HUMAN] Plays a role in the physiological regulation of the intracellular CoA concentration (By similarity).
==See Also==
==See Also==
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*[[Pantothenate kinase|Pantothenate kinase]]
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*[[Pantothenate kinase 3D structures|Pantothenate kinase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Pantothenate kinase]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Arrowsmith CH]]
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[[Category: Bolshan, Y.]]
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[[Category: Bolshan Y]]
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[[Category: Bountra, C.]]
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[[Category: Bountra C]]
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[[Category: Edwards, A M.]]
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[[Category: Edwards AM]]
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[[Category: Hong, B.]]
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[[Category: Hong B]]
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[[Category: Mottaghi, K.]]
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[[Category: Mottaghi K]]
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[[Category: Park, H.]]
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[[Category: Park H]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Smil D]]
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[[Category: Smil, D.]]
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[[Category: Tempel W]]
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[[Category: Tempel, W.]]
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[[Category: Weigelt J]]
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[[Category: Weigelt, J.]]
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[[Category: Wernimont AK]]
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[[Category: Wernimont, A K.]]
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[[Category: Sgc]]
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[[Category: Structural genomics consortium]]
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[[Category: Transferase]]
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Current revision

Human Pantothenate kinase 3 in complex with a pantothenate analog

PDB ID 3sms

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