3s3x
From Proteopedia
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==Structure of chicken acid-sensing ion channel 1 AT 3.0 A resolution in complex with psalmotoxin== | ==Structure of chicken acid-sensing ion channel 1 AT 3.0 A resolution in complex with psalmotoxin== | ||
| - | <StructureSection load='3s3x' size='340' side='right' caption='[[3s3x]], [[Resolution|resolution]] 2.99Å' scene=''> | + | <StructureSection load='3s3x' size='340' side='right'caption='[[3s3x]], [[Resolution|resolution]] 2.99Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3s3x]] is a 6 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3s3x]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [https://en.wikipedia.org/wiki/Psalmopoeus_cambridgei Psalmopoeus cambridgei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S3X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S3X FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.99Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | <tr | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s3x OCA], [https://pdbe.org/3s3x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s3x RCSB], [https://www.ebi.ac.uk/pdbsum/3s3x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s3x ProSAT]</span></td></tr> |
| - | + | </table> | |
| - | <table> | + | == Function == |
| + | [https://www.uniprot.org/uniprot/ASIC1_CHICK ASIC1_CHICK] Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride (By similarity).<ref>PMID:16002453</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Structure of the Acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1.,Dawson RJ, Benz J, Stohler P, Tetaz T, Joseph C, Huber S, Schmid G, Hugin D, Pflimlin P, Trube G, Rudolph MG, Hennig M, Ruf A Nat Commun. 2012 Jul 3;3:936. doi: 10.1038/ncomms1917. PMID:22760635<ref>PMID:22760635</ref> | Structure of the Acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1.,Dawson RJ, Benz J, Stohler P, Tetaz T, Joseph C, Huber S, Schmid G, Hugin D, Pflimlin P, Trube G, Rudolph MG, Hennig M, Ruf A Nat Commun. 2012 Jul 3;3:936. doi: 10.1038/ncomms1917. PMID:22760635<ref>PMID:22760635</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
| + | <div class="pdbe-citations 3s3x" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Ion channels|Ion channels]] | + | *[[Ion channels 3D structures|Ion channels 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Gallus gallus]] | [[Category: Gallus gallus]] | ||
| - | [[Category: Benz | + | [[Category: Large Structures]] |
| - | [[Category: Dawson | + | [[Category: Psalmopoeus cambridgei]] |
| - | [[Category: Hennig | + | [[Category: Benz J]] |
| - | [[Category: Huber | + | [[Category: Dawson RJP]] |
| - | [[Category: Huegin | + | [[Category: Hennig M]] |
| - | [[Category: Joseph | + | [[Category: Huber S]] |
| - | [[Category: Pflimlin | + | [[Category: Huegin D]] |
| - | [[Category: Rudolph | + | [[Category: Joseph C]] |
| - | [[Category: Ruf | + | [[Category: Pflimlin P]] |
| - | [[Category: Schmid | + | [[Category: Rudolph MG]] |
| - | [[Category: Stohler | + | [[Category: Ruf A]] |
| - | [[Category: Tetaz | + | [[Category: Schmid G]] |
| - | [[Category: Trube | + | [[Category: Stohler P]] |
| - | + | [[Category: Tetaz T]] | |
| - | + | [[Category: Trube G]] | |
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Current revision
Structure of chicken acid-sensing ion channel 1 AT 3.0 A resolution in complex with psalmotoxin
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Categories: Gallus gallus | Large Structures | Psalmopoeus cambridgei | Benz J | Dawson RJP | Hennig M | Huber S | Huegin D | Joseph C | Pflimlin P | Rudolph MG | Ruf A | Schmid G | Stohler P | Tetaz T | Trube G
