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3v71
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==Crystal structure of PUF-6 in complex with 5BE13 RNA== | ==Crystal structure of PUF-6 in complex with 5BE13 RNA== | ||
| - | <StructureSection load='3v71' size='340' side='right' caption='[[3v71]], [[Resolution|resolution]] 2.90Å' scene=''> | + | <StructureSection load='3v71' size='340' side='right'caption='[[3v71]], [[Resolution|resolution]] 2.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3v71]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3v71]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V71 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V71 FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.902Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr> | |
| - | <tr><td class="sblockLbl"><b>[[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v71 OCA], [https://pdbe.org/3v71 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v71 RCSB], [https://www.ebi.ac.uk/pdbsum/3v71 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v71 ProSAT]</span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </table> |
| - | <table> | + | == Function == |
| + | [https://www.uniprot.org/uniprot/PUF7_CAEEL PUF7_CAEEL] RNA-binding protein that binds to the consensus sequence 5'-CUCUGUAUCUUGU-3' in mRNA 3'-UTRs and modulates mRNA expression and stability. Functions redundantly with puf-5 and puf-6 in oocyte formation and organization, early embryonic cell divisions, and repression of expression of glp-1 and other maternal mRNAs in late oogenesis.<ref>PMID:17234175</ref> <ref>PMID:22205700</ref> <ref>PMID:22542599</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Caenorhabditis elegans]] | [[Category: Caenorhabditis elegans]] | ||
| - | [[Category: Hall | + | [[Category: Large Structures]] |
| - | [[Category: Holley | + | [[Category: Hall TMT]] |
| - | [[Category: Keles | + | [[Category: Holley CH]] |
| - | [[Category: Kershner | + | [[Category: Keles S]] |
| - | [[Category: Kimble | + | [[Category: Kershner A]] |
| - | [[Category: Qiu | + | [[Category: Kimble J]] |
| - | [[Category: Wang | + | [[Category: Qiu C]] |
| - | [[Category: Wickens | + | [[Category: Wang Y]] |
| - | [[Category: Wilinski | + | [[Category: Wickens M]] |
| - | + | [[Category: Wilinski D]] | |
| - | + | ||
Current revision
Crystal structure of PUF-6 in complex with 5BE13 RNA
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Categories: Caenorhabditis elegans | Large Structures | Hall TMT | Holley CH | Keles S | Kershner A | Kimble J | Qiu C | Wang Y | Wickens M | Wilinski D
