3utl

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==Human pepsin 3b==
==Human pepsin 3b==
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<StructureSection load='3utl' size='340' side='right' caption='[[3utl]], [[Resolution|resolution]] 2.61&Aring;' scene=''>
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<StructureSection load='3utl' size='340' side='right'caption='[[3utl]], [[Resolution|resolution]] 2.61&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3utl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UTL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UTL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3utl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UTL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UTL FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pepsin_A Pepsin A], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.1 3.4.23.1] </span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.61&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3utl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3utl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3utl RCSB], [http://www.ebi.ac.uk/pdbsum/3utl PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3utl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3utl OCA], [https://pdbe.org/3utl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3utl RCSB], [https://www.ebi.ac.uk/pdbsum/3utl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3utl ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PEPA4_HUMAN PEPA4_HUMAN] Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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An analysis of subdomain orientation, conformational change and disorder in relation to crystal packing of aspartic proteinases.,Bailey D, Carpenter EP, Coker A, Coker S, Read J, Jones AT, Erskine P, Aguilar CF, Badasso M, Toldo L, Rippmann F, Sanz-Aparicio J, Albert A, Blundell TL, Roberts NB, Wood SP, Cooper JB Acta Crystallogr D Biol Crystallogr. 2012 May;68(Pt 5):541-52. Epub 2012 Apr 17. PMID:22525752<ref>PMID:22525752</ref>
An analysis of subdomain orientation, conformational change and disorder in relation to crystal packing of aspartic proteinases.,Bailey D, Carpenter EP, Coker A, Coker S, Read J, Jones AT, Erskine P, Aguilar CF, Badasso M, Toldo L, Rippmann F, Sanz-Aparicio J, Albert A, Blundell TL, Roberts NB, Wood SP, Cooper JB Acta Crystallogr D Biol Crystallogr. 2012 May;68(Pt 5):541-52. Epub 2012 Apr 17. PMID:22525752<ref>PMID:22525752</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3utl" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Pepsin A]]
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[[Category: Large Structures]]
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[[Category: Coker, A.]]
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[[Category: Coker A]]
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[[Category: Cooper, J B.]]
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[[Category: Cooper JB]]
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[[Category: Aspartic proteinase]]
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[[Category: Hydrolase]]
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[[Category: Stomach lumen]]
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Current revision

Human pepsin 3b

PDB ID 3utl

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