3tck

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==Crystal structure of Peptidyl-tRNA hydrolase from Mycobacterium tuberculosis - Form 4==
==Crystal structure of Peptidyl-tRNA hydrolase from Mycobacterium tuberculosis - Form 4==
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<StructureSection load='3tck' size='340' side='right' caption='[[3tck]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='3tck' size='340' side='right'caption='[[3tck]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3tck]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TCK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TCK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3tck]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TCK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TCK FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3tcn|3tcn]], [[2z2i|2z2i]], [[2z2j|2z2j]], [[2z2k|2z2k]], [[2pth|2pth]], [[2jrc|2jrc]], [[3p2j|3p2j]], [[3td2|3td2]], [[3td6|3td6]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MT1042, MTCY10G2.35, pth, Rv1014c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tck FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tck OCA], [https://pdbe.org/3tck PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tck RCSB], [https://www.ebi.ac.uk/pdbsum/3tck PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tck ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aminoacyl-tRNA_hydrolase Aminoacyl-tRNA hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.29 3.1.1.29] </span></td></tr>
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</table>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tck FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tck OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tck RCSB], [http://www.ebi.ac.uk/pdbsum/3tck PDBsum]</span></td></tr>
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== Function ==
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<table>
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[https://www.uniprot.org/uniprot/PTH_MYCTU PTH_MYCTU] The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Structures of new crystal forms of Mycobacterium tuberculosis peptidyl-tRNA hydrolase and functionally important plasticity of the molecule.,Selvaraj M, Ahmad R, Varshney U, Vijayan M Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Feb 1;68(Pt, 2):124-8. Epub 2012 Jan 21. PMID:22297982<ref>PMID:22297982</ref>
Structures of new crystal forms of Mycobacterium tuberculosis peptidyl-tRNA hydrolase and functionally important plasticity of the molecule.,Selvaraj M, Ahmad R, Varshney U, Vijayan M Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Feb 1;68(Pt, 2):124-8. Epub 2012 Jan 21. PMID:22297982<ref>PMID:22297982</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3tck" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Aminoacyl-tRNA hydrolase]]
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[[Category: Large Structures]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Ahmad, R.]]
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[[Category: Ahmad R]]
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[[Category: Selvaraj, M.]]
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[[Category: Selvaraj M]]
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[[Category: Varshney, U.]]
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[[Category: Varshney U]]
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[[Category: Vijayan, M.]]
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[[Category: Vijayan M]]
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[[Category: Cytosol]]
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[[Category: Hydrolase]]
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[[Category: Hydrolysis of peptidyl-trna]]
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[[Category: Peptidyl-trna]]
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[[Category: Pth]]
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Current revision

Crystal structure of Peptidyl-tRNA hydrolase from Mycobacterium tuberculosis - Form 4

PDB ID 3tck

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