4f40
From Proteopedia
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==X-ray crystal structure of Apo prostaglandin f synthase from Leishmania major Friedlin== | ==X-ray crystal structure of Apo prostaglandin f synthase from Leishmania major Friedlin== | ||
| - | <StructureSection load='4f40' size='340' side='right' caption='[[4f40]], [[Resolution|resolution]] 1.60Å' scene=''> | + | <StructureSection load='4f40' size='340' side='right'caption='[[4f40]], [[Resolution|resolution]] 1.60Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4f40]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4f40]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F40 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F40 FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | |
| - | < | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f40 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f40 OCA], [https://pdbe.org/4f40 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f40 RCSB], [https://www.ebi.ac.uk/pdbsum/4f40 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f40 ProSAT]</span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </table> |
| - | <table> | + | == Function == |
| + | [https://www.uniprot.org/uniprot/PGFS_LEIMA PGFS_LEIMA] Catalyzes the NADP-dependent formation of prostaglandin F2-alpha from prostaglandin H2. Has also aldo/ketoreductase activity toward the synthetic substrates 9,10-phenanthrenequinone and p-nitrobenzaldehyde.<ref>PMID:12633659</ref> | ||
==See Also== | ==See Also== | ||
| - | *[[Prostaglandin F synthase|Prostaglandin F synthase]] | + | *[[Prostaglandin F synthase 3D structures|Prostaglandin F synthase 3D structures]] |
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Leishmania major]] | [[Category: Leishmania major]] | ||
| - | [[Category: Prostaglandin-F synthase]] | ||
| - | [[Category: SSGCID, Seattle Structural Genomics Center for Infectious Disease.]] | ||
| - | [[Category: Nadp]] | ||
| - | [[Category: National institute of allergy and infectious disease]] | ||
| - | [[Category: Niaid]] | ||
| - | [[Category: Oxidoreductase]] | ||
| - | [[Category: Seattle structural genomics center for infectious disease]] | ||
| - | [[Category: Ssgcid]] | ||
| - | [[Category: Structural genomic]] | ||
Current revision
X-ray crystal structure of Apo prostaglandin f synthase from Leishmania major Friedlin
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