4a4f
From Proteopedia
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==Solution structure of SPF30 Tudor domain in complex with symmetrically dimethylated arginine== | ==Solution structure of SPF30 Tudor domain in complex with symmetrically dimethylated arginine== | ||
| - | <StructureSection load='4a4f' size='340' side='right' caption='[[4a4f]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='4a4f' size='340' side='right'caption='[[4a4f]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4a4f]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4a4f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A4F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A4F FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2MR:N3,+N4-DIMETHYLARGININE'>2MR</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2MR:N3,+N4-DIMETHYLARGININE'>2MR</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4a4e|4a4e]], [[4a4g|4a4g]], [[4a4h|4a4h]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4a4e|4a4e]], [[4a4g|4a4g]], [[4a4h|4a4h]]</div></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a4f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a4f OCA], [https://pdbe.org/4a4f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a4f RCSB], [https://www.ebi.ac.uk/pdbsum/4a4f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a4f ProSAT]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/SPF30_HUMAN SPF30_HUMAN]] Necessary for spliceosome assembly. Overexpression causes apoptosis.<ref>PMID:9817934</ref> <ref>PMID:11331595</ref> <ref>PMID:11331295</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4a4f" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
| - | [[Category: Englbrecht, C | + | [[Category: Large Structures]] |
| - | [[Category: Fessas, D | + | [[Category: Englbrecht, C]] |
| - | [[Category: Fischer, U | + | [[Category: Fessas, D]] |
| - | [[Category: Machyna, M | + | [[Category: Fischer, U]] |
| - | [[Category: Madl, T | + | [[Category: Machyna, M]] |
| - | [[Category: Neugebauer, K M | + | [[Category: Madl, T]] |
| - | [[Category: Sattler, M | + | [[Category: Neugebauer, K M]] |
| - | [[Category: Tripsianes, K | + | [[Category: Sattler, M]] |
| + | [[Category: Tripsianes, K]] | ||
[[Category: Rna binding protein]] | [[Category: Rna binding protein]] | ||
Current revision
Solution structure of SPF30 Tudor domain in complex with symmetrically dimethylated arginine
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