2xsl

<StructureSection load='2xsl' size='340' side='right' caption='[[2xsl]], [[Resolution|resolution]] 1.59&Aring;' scene=''>

<table><tr><td colspan='2'>[[2xsl]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XSL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XSL FirstGlance]. <br>

</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xsl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xsl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xsl RCSB], [http://www.ebi.ac.uk/pdbsum/2xsl PDBsum]</span></td></tr>

tRNAs are aminoacylated with the correct amino acid by the cognate aminoacyl-tRNA synthetase. The tRNA/synthetase systems can be divided into two classes: class I and class II. Within class I, the tRNA identity elements that enable the specificity consist of complex sequence and structure motifs, whereas in class II the identity elements are assured by few and simple determinants, which are mostly located in the tRNA acceptor stem. The tRNA(Gly)/glycyl-tRNA-synthetase (GlyRS) system is a special case regarding evolutionary aspects. There exist two different types of GlyRS, namely an archaebacterial/human type and an eubacterial type, reflecting the evolutionary divergence within this system. We previously reported the crystal structures of an Escherichia coli and of a human tRNA(Gly) acceptor stem microhelix. Here we present the crystal structure of a thermophilic tRNA(Gly) aminoacyl stem from Thermus thermophilus at 1.6A resolution and provide insight into the RNA geometry and hydration.

 

The crystal structure of a Thermus thermophilus tRNA(Gly) acceptor stem microhelix at 1.6 A resolution.,Oberthur D, Eichert A, Erdmann VA, Furste JP, Betzel Ch, Forster C Biochem Biophys Res Commun. 2011 Jan 7;404(1):245-9. Epub 2010 Nov 27. PMID:21114959<ref>PMID:21114959</ref>

 

</div>

<references/>

[[Category: Betzel, C.]]

[[Category: Eichert, A.]]

[[Category: Erdmann, V A.]]

[[Category: Foerster, C.]]

[[Category: Fuerste, J P.]]

[[Category: Oberthuer, D.]]

[[Category: Identity element]]

[[Category: Rna]]

[[Category: Rna hydration]]