User:John S. de Banzie/Sandbox 2

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==RNA Stem and Loop Structure==
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==Zinc Finger==
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<StructureSection load='2qh2' size='400' side='right' caption='RNA hairpin loop from human telomerase RNA, [[2qh2]]' scene='59/590622/2qh2stick/1'>
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<StructureSection load='1mey' size='400' side='right' caption='Leucine Zipper, [[1mey]]' scene='59/590622/1meyspacefill/1'>
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Intramolecular hydrogen bonding in RNA molecules results in the formation of stem and loop (also known as hairpin loop) structures.
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This zinc finger protein has one subunit. <scene name='59/590622/1meyspacefillunits/1'>Three zinc finger motifs</scene> fit into a major groove in the DNA. Each consists of an <scene name='59/590622/1meycartoon/1'>alpha helix, two short segments of beta pleated sheet, and a zinc ion (violet)</scene>.
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Note that the stem portion is a double stranded <scene name='59/590622/2qh2stickends/1'>antiparallel</scene> right-handed helix with both <scene name='59/590622/2qh2spacefill/1'>major and minor grooves</scene>. Note also that the structure is not the same as that of DNA.
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Note the <scene name='59/590622/2qh2bases/1'>complementary base pairing</scene> in the stem (A: red, C: green, G: orange, T: blue) and the unpaired bases in the loop.
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(The stem and loop structure shown is part of the RNA in human telomerase. Telomerase protects chromosomes by restoring DNA that is lost from the ends during DNA replication. The RNA is used as a template and the enzyme is thus an internally templated RNA-dependant DNA polymerase.)
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</StructureSection>
</StructureSection>
== References ==
== References ==
<references/>
<references/>

Current revision

Zinc Finger

Leucine Zipper, 1mey

Drag the structure with the mouse to rotate

References

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John S. de Banzie

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