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4tps
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4tps is ON HOLD Authors: Jameson, K.H., Turkenburg, J.P., Fogg, M.J., Grahl.A., Wilkinson, A.J. Description: Sporulation Inhibitor of DNA Replicati...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Sporulation Inhibitor of DNA Replication, SirA, in complex with Domain I of DnaA== | |
| + | <StructureSection load='4tps' size='340' side='right'caption='[[4tps]], [[Resolution|resolution]] 1.65Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4tps]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TPS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TPS FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4tps FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tps OCA], [https://pdbe.org/4tps PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4tps RCSB], [https://www.ebi.ac.uk/pdbsum/4tps PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4tps ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SIRA_BACSU SIRA_BACSU] Inhibits DNA replication in growing cells, thus reducing chromosome copy number and playing a significant role during the onset of sporulation. | ||
| - | + | ==See Also== | |
| - | + | *[[DnaA|DnaA]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Bacillus subtilis subsp. subtilis str. 168]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Fogg MJ]] | ||
| + | [[Category: Grahl A]] | ||
| + | [[Category: Jameson KH]] | ||
| + | [[Category: Turkenburg JP]] | ||
| + | [[Category: Wilkinson AJ]] | ||
Current revision
Sporulation Inhibitor of DNA Replication, SirA, in complex with Domain I of DnaA
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