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4cym

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==Complex of human VARP-ANKRD1 with Rab32-GppCp==
==Complex of human VARP-ANKRD1 with Rab32-GppCp==
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<StructureSection load='4cym' size='340' side='right' caption='[[4cym]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='4cym' size='340' side='right'caption='[[4cym]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4cym]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CYM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CYM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4cym]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CYM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CYM FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GCP:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>GCP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cz2|4cz2]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GCP:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>GCP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Small_monomeric_GTPase Small monomeric GTPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.5.2 3.6.5.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cym OCA], [https://pdbe.org/4cym PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cym RCSB], [https://www.ebi.ac.uk/pdbsum/4cym PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cym ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cym OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cym RCSB], [http://www.ebi.ac.uk/pdbsum/4cym PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/RAB32_HUMAN RAB32_HUMAN] Acts as an A-kinase anchoring protein by binding to the type II regulatory subunit of protein kinase A and anchoring it to the mitochondrion. Also involved in synchronization of mitochondrial fission. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.<ref>PMID:12186851</ref> <ref>PMID:21255211</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4cym" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Ankyrin repeat domain-containing protein 3D structures|Ankyrin repeat domain-containing protein 3D structures]]
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*[[Ras-related protein Rab 3D structures|Ras-related protein Rab 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Small monomeric GTPase]]
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[[Category: Homo sapiens]]
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[[Category: Evans, P R.]]
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[[Category: Large Structures]]
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[[Category: McCoy, A J.]]
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[[Category: Evans PR]]
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[[Category: Owen, D J.]]
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[[Category: McCoy AJ]]
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[[Category: Perez-Dorado, I.]]
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[[Category: Owen DJ]]
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[[Category: Schaefer, I B.]]
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[[Category: Perez-Dorado I]]
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[[Category: Endosome]]
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[[Category: Schaefer IB]]
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[[Category: Melanosome biogenesis]]
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[[Category: Rab]]
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[[Category: Rab-effector]]
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[[Category: Transport protein]]
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[[Category: Varp]]
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[[Category: Vesicle trafficking]]
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Current revision

Complex of human VARP-ANKRD1 with Rab32-GppCp

PDB ID 4cym

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