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4qmi
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The XMAP215 family drives microtubule polymerization using a structurally diverse TOG array== |
| - | + | <StructureSection load='4qmi' size='340' side='right'caption='[[4qmi]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4qmi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QMI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QMI FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qmi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qmi OCA], [https://pdbe.org/4qmi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qmi RCSB], [https://www.ebi.ac.uk/pdbsum/4qmi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qmi ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CKAP5_HUMAN CKAP5_HUMAN] Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles.<ref>PMID:12569123</ref> <ref>PMID:21646404</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Currie JD]] | ||
| + | [[Category: Fox JC]] | ||
| + | [[Category: Howard AE]] | ||
| + | [[Category: Rogers SL]] | ||
| + | [[Category: Slep KC]] | ||
Current revision
The XMAP215 family drives microtubule polymerization using a structurally diverse TOG array
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Categories: Homo sapiens | Large Structures | Currie JD | Fox JC | Howard AE | Rogers SL | Slep KC
