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4g89
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==Crystal structure of k. pneumoniae mta/adohcy nucleosidase in complex with fragmented s-adenosyl-l-homocysteine== | ==Crystal structure of k. pneumoniae mta/adohcy nucleosidase in complex with fragmented s-adenosyl-l-homocysteine== | ||
| - | <StructureSection load='4g89' size='340' side='right' caption='[[4g89]], [[Resolution|resolution]] 2.10Å' scene=''> | + | <StructureSection load='4g89' size='340' side='right'caption='[[4g89]], [[Resolution|resolution]] 2.10Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4g89]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4g89]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae_subsp._pneumoniae_MGH_78578 Klebsiella pneumoniae subsp. pneumoniae MGH 78578]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G89 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4G89 FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | <tr | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4g89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g89 OCA], [https://pdbe.org/4g89 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4g89 RCSB], [https://www.ebi.ac.uk/pdbsum/4g89 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4g89 ProSAT]</span></td></tr> |
| - | + | </table> | |
| - | <table> | + | == Function == |
| + | [https://www.uniprot.org/uniprot/MTNN_KLEP7 MTNN_KLEP7] Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity). | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Klebsiella pneumoniae subsp. pneumoniae MGH 78578]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Anderson | + | [[Category: Anderson BF]] |
| - | [[Category: Brown | + | [[Category: Brown RL]] |
| - | [[Category: Evans | + | [[Category: Evans GB]] |
| - | [[Category: Norris | + | [[Category: Norris GE]] |
| - | [[Category: Tyler | + | [[Category: Tyler PC]] |
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Current revision
Crystal structure of k. pneumoniae mta/adohcy nucleosidase in complex with fragmented s-adenosyl-l-homocysteine
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