This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4qkv

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:59, 20 March 2024) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 4qkv is ON HOLD until Paper Publication
+
==Crystal structure of the mouse cavin1 HR1 domain==
-
 
+
<StructureSection load='4qkv' size='340' side='right'caption='[[4qkv]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
-
Authors: Kovtun, O., Tillu, V., Parton, R.G., Collins, B.M.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[4qkv]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QKV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QKV FirstGlance]. <br>
-
Description: Crystal structure of the mouse cavin1 HR1 domain
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qkv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qkv OCA], [https://pdbe.org/4qkv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qkv RCSB], [https://www.ebi.ac.uk/pdbsum/4qkv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qkv ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CAVN1_MOUSE CAVN1_MOUSE] Plays an important role in caveolae formation and organization. Essential for the formation of caveolae in all tissues (PubMed:18191225, PubMed:18840361, PubMed:18056712, PubMed:30188967). Core component of the CAVIN complex which is essential for recruitment of the complex to the caveolae in presence of calveolin-1 (CAV1) (PubMed:19546242). Essential for normal oligomerization of CAV1 (PubMed:23652019). Promotes ribosomal transcriptional activity in response to metabolic challenges in the adipocytes and plays an important role in the formation of the ribosomal transcriptional loop (PubMed:27528195). Dissociates transcription complexes paused by DNA-bound TTF1, thereby releasing both RNA polymerase I and pre-RNA from the template (PubMed:9582279, PubMed:11139612). The caveolae biogenesis pathway is required for the secretion of proteins such as GASK1A (PubMed:30188967).<ref>PMID:11139612</ref> <ref>PMID:18056712</ref> <ref>PMID:18191225</ref> <ref>PMID:18840361</ref> <ref>PMID:19546242</ref> <ref>PMID:23652019</ref> <ref>PMID:27528195</ref> <ref>PMID:30188967</ref> <ref>PMID:9582279</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
 +
[[Category: Mus musculus]]
 +
[[Category: Collins BM]]
 +
[[Category: Kovtun O]]
 +
[[Category: Parton RG]]
 +
[[Category: Tillu V]]

Current revision

Crystal structure of the mouse cavin1 HR1 domain

PDB ID 4qkv

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4qkv"
Personal tools