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4qoh
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of fad quinone reductase 2 in complex with resveratrol at 1.6A== | |
| + | <StructureSection load='4qoh' size='340' side='right'caption='[[4qoh]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4qoh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QOH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QOH FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=STL:RESVERATROL'>STL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qoh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qoh OCA], [https://pdbe.org/4qoh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qoh RCSB], [https://www.ebi.ac.uk/pdbsum/4qoh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qoh ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/NQO2_HUMAN NQO2_HUMAN] The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.<ref>PMID:18254726</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Quinone reductase|Quinone reductase]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Antoine M]] | ||
| + | [[Category: Boutin JA]] | ||
| + | [[Category: Ferry G]] | ||
| + | [[Category: Isabet T]] | ||
| + | [[Category: Serriere J]] | ||
Current revision
Crystal structure of fad quinone reductase 2 in complex with resveratrol at 1.6A
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