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1ccn

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[[Image:1ccn.jpg|left|200px]]
 
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{{Structure
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==DIRECT NOE REFINEMENT OF CRAMBIN FROM 2D NMR DATA USING A SLOW-COOLING ANNEALING PROTOCOL==
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|PDB= 1ccn |SIZE=350|CAPTION= <scene name='initialview01'>1ccn</scene>
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<StructureSection load='1ccn' size='340' side='right'caption='[[1ccn]]' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[1ccn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Crambe_hispanica_subsp._abyssinica Crambe hispanica subsp. abyssinica]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CCN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CCN FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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|GENE=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ccn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ccn OCA], [https://pdbe.org/1ccn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ccn RCSB], [https://www.ebi.ac.uk/pdbsum/1ccn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ccn ProSAT]</span></td></tr>
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}}
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</table>
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== Function ==
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'''DIRECT NOE REFINEMENT OF CRAMBIN FROM 2D NMR DATA USING A SLOW-COOLING ANNEALING PROTOCOL'''
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[https://www.uniprot.org/uniprot/CRAM_CRAAB CRAM_CRAAB] The function of this hydrophobic plant seed protein is not known.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==Overview==
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Check<jmol>
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A set of computer programs called DINOSAUR has been developed, which allows the refinement of biomolecular structures directly from 2D NOE intensities. The NOE restraining potential implemented emphasises the weak intensities corresponding to larger distances which are more likely to determine the three-dimensional structure. An approximation based on a two-spin approximation is proposed for the gradient of the NOE intensities instead of the exact solution which is extremely time-consuming. The DINOSAUR routines have been implemented in various refinement programs (Distance bound Driven Dynamics, Molecular Dynamics and Energy Minimisation) and tested on an eight-residue model peptide.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cc/1ccn_consurf.spt"</scriptWhenChecked>
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==About this Structure==
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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1CCN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Crambe_hispanica_subsp._abyssinica Crambe hispanica subsp. abyssinica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CCN OCA].
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==Reference==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ccn ConSurf].
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Direct NOE refinement of biomolecular structures using 2D NMR data., Bonvin AM, Boelens R, Kaptein R, J Biomol NMR. 1991 Sep;1(3):305-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1841701 1841701]
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Crambe hispanica subsp. abyssinica]]
[[Category: Crambe hispanica subsp. abyssinica]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Boelens, R.]]
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[[Category: Boelens R]]
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[[Category: Bonvin, A M.J J.]]
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[[Category: Bonvin AMJJ]]
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[[Category: Kaptein, R.]]
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[[Category: Kaptein R]]
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[[Category: Lamerichs, R M.J N.]]
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[[Category: Lamerichs RMJN]]
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[[Category: Rullmann, J A.C.]]
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[[Category: Rullmann JAC]]
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[[Category: plant seed protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:22:41 2008''
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Current revision

DIRECT NOE REFINEMENT OF CRAMBIN FROM 2D NMR DATA USING A SLOW-COOLING ANNEALING PROTOCOL

PDB ID 1ccn

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