4o55

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==HIV-1 Integrase Catalytic Core Domain Complexed with Allosteric Inhibitor (2S)-tert-butoxy[6-(5-chloro-1H-benzimidazol-2-yl)-2,5-dimethyl-4-phenylpyridin-3-yl]ethanoic acid==
==HIV-1 Integrase Catalytic Core Domain Complexed with Allosteric Inhibitor (2S)-tert-butoxy[6-(5-chloro-1H-benzimidazol-2-yl)-2,5-dimethyl-4-phenylpyridin-3-yl]ethanoic acid==
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<StructureSection load='4o55' size='340' side='right' caption='[[4o55]], [[Resolution|resolution]] 2.24&Aring;' scene=''>
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<StructureSection load='4o55' size='340' side='right'caption='[[4o55]], [[Resolution|resolution]] 2.24&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4o55]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O55 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4O55 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4o55]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_1_(NEW_YORK-5_ISOLATE) Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O55 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4O55 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LF9:(2S)-TERT-BUTOXY[6-(5-CHLORO-1H-BENZIMIDAZOL-2-YL)-2,5-DIMETHYL-4-PHENYLPYRIDIN-3-YL]ETHANOIC+ACID'>LF9</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.24&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAF:S-DIMETHYLARSINOYL-CYSTEINE'>CAF</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CAF:S-DIMETHYLARSINOYL-CYSTEINE'>CAF</scene>, <scene name='pdbligand=LF9:(2S)-TERT-BUTOXY[6-(5-CHLORO-1H-BENZIMIDAZOL-2-YL)-2,5-DIMETHYL-4-PHENYLPYRIDIN-3-YL]ETHANOIC+ACID'>LF9</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1itg|1itg]], [[4o0j|4o0j]], [[4o5b|4o5b]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4o55 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o55 OCA], [https://pdbe.org/4o55 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4o55 RCSB], [https://www.ebi.ac.uk/pdbsum/4o55 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4o55 ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o55 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o55 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4o55 RCSB], [http://www.ebi.ac.uk/pdbsum/4o55 PDBsum]</span></td></tr>
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</table>
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<table>
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<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4o55" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Retroviral integrase 3D structures|Retroviral integrase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Feng, L.]]
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[[Category: Large Structures]]
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[[Category: Kvaratskhelia, M.]]
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[[Category: Feng L]]
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[[Category: Allosteric inhibitor]]
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[[Category: Kvaratskhelia M]]
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[[Category: Ccd]]
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[[Category: Dde motif]]
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[[Category: Hiv integrase]]
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[[Category: Viral protein-inhibitor complex]]
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Current revision

HIV-1 Integrase Catalytic Core Domain Complexed with Allosteric Inhibitor (2S)-tert-butoxy[6-(5-chloro-1H-benzimidazol-2-yl)-2,5-dimethyl-4-phenylpyridin-3-yl]ethanoic acid

PDB ID 4o55

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