4qre
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4qre is ON HOLD Authors: Hilgers, M.T. Description: Discovery and SAR of a Novel Series of Pyrimidine Antibacterials Targeting Methionyl-tRNA Synth...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of Methionyl-tRNA Synthetase in complex with 1-(4-{4-[(1H-benzimidazol-2-ylmethyl)amino]-6-(4,5-dimethoxy-2-methylphenoxy)pyrimidin-2-yl}piperazin-1-yl)ethanone== | |
| + | <StructureSection load='4qre' size='340' side='right'caption='[[4qre]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4qre]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QRE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QRE FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3BG:1-(4-{4-[(1H-BENZIMIDAZOL-2-YLMETHYL)AMINO]-6-(4,5-DIMETHOXY-2-METHYLPHENOXY)PYRIMIDIN-2-YL}PIPERAZIN-1-YL)ETHANONE'>3BG</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qre FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qre OCA], [https://pdbe.org/4qre PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qre RCSB], [https://www.ebi.ac.uk/pdbsum/4qre PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qre ProSAT]</span></td></tr> | ||
| + | </table> | ||
| - | + | ==See Also== | |
| - | + | *[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Staphylococcus aureus]] | ||
| + | [[Category: Hilgers MT]] | ||
Current revision
Structure of Methionyl-tRNA Synthetase in complex with 1-(4-{4-[(1H-benzimidazol-2-ylmethyl)amino]-6-(4,5-dimethoxy-2-methylphenoxy)pyrimidin-2-yl}piperazin-1-yl)ethanone
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