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3j7a

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==Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, small subunit==
==Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, small subunit==
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<StructureSection load='3j7a' size='340' side='right' caption='[[3j7a]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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<SX load='3j7a' size='340' side='right' viewer='molstar' caption='[[3j7a]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3j7a]] is a 33 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J7A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3J7A FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3j7a]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J7A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J7A FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=34G:EMETINE'>34G</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3j79|3j79]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=34G:EMETINE'>34G</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3j7a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j7a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3j7a RCSB], [http://www.ebi.ac.uk/pdbsum/3j7a PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j7a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j7a OCA], [https://pdbe.org/3j7a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j7a RCSB], [https://www.ebi.ac.uk/pdbsum/3j7a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j7a ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RS3A_PLAF7 RS3A_PLAF7]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3j7a" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Ribosome 3D structures|Ribosome 3D structures]]
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*[[Transfer RNA (tRNA)|Transfer RNA (tRNA)]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
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</StructureSection>
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</SX>
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[[Category: Plasmodium falciparum]]
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[[Category: Large Structures]]
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[[Category: Bai, X C.]]
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[[Category: Plasmodium falciparum 3D7]]
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[[Category: Baum, J.]]
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[[Category: Bai XC]]
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[[Category: Brown, A.]]
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[[Category: Baum J]]
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[[Category: Condron, M.]]
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[[Category: Brown A]]
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[[Category: Fernandez, I S.]]
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[[Category: Condron M]]
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[[Category: Hanssen, E.]]
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[[Category: Fernandez IS]]
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[[Category: Scheres, S H.W.]]
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[[Category: Hanssen E]]
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[[Category: Tan, Y H.]]
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[[Category: Scheres SHW]]
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[[Category: Wong, W.]]
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[[Category: Tan YH]]
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[[Category: Emetine]]
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[[Category: Wong W]]
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[[Category: Ribosome-inhibitor complex]]
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Current revision

Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, small subunit

3j7a, resolution 3.20Å

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