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4ntk

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==QueD from E. coli==
==QueD from E. coli==
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<StructureSection load='4ntk' size='340' side='right' caption='[[4ntk]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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<StructureSection load='4ntk' size='340' side='right'caption='[[4ntk]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4ntk]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NTK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NTK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4ntk]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NTK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NTK FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=ZSP:2-AMINO-6-[(1Z)-1,2-DIHYDROXYPROP-1-EN-1-YL]-7,8-DIHYDROPTERIDIN-4(3H)-ONE'>ZSP</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ntn|4ntn]], [[4ntm|4ntm]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=ZSP:2-AMINO-6-[(1Z)-1,2-DIHYDROXYPROP-1-EN-1-YL]-7,8-DIHYDROPTERIDIN-4(3H)-ONE'>ZSP</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/6-carboxytetrahydropterin_synthase 6-carboxytetrahydropterin synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.50 4.1.2.50] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ntk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ntk OCA], [https://pdbe.org/4ntk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ntk RCSB], [https://www.ebi.ac.uk/pdbsum/4ntk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ntk ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ntk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ntk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ntk RCSB], [http://www.ebi.ac.uk/pdbsum/4ntk PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/QUED_ECOLI QUED_ECOLI] Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde. Can also convert 6-pyruvoyltetrahydropterin (PPH4) and sepiapterin to CPH4; these 2 compounds are probably intermediates in the reaction from H2NTP.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 6-carboxytetrahydropterin synthase]]
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[[Category: Escherichia coli K-12]]
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[[Category: Bandarian, V.]]
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[[Category: Large Structures]]
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[[Category: Miles, Z D.]]
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[[Category: Bandarian V]]
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[[Category: Roberts, S A.]]
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[[Category: Miles ZD]]
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[[Category: 6-ptp]]
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[[Category: Roberts SA]]
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[[Category: C27a]]
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[[Category: Lyase]]
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[[Category: Queuosine biosynthesis enzyme]]
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[[Category: Sepiapterin]]
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[[Category: T-fold]]
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QueD from E. coli

PDB ID 4ntk

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