We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

4oy2

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (00:37, 28 December 2023) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Crystal structure of TAF1-TAF7, a TFIID subcomplex==
==Crystal structure of TAF1-TAF7, a TFIID subcomplex==
-
<StructureSection load='4oy2' size='340' side='right' caption='[[4oy2]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
+
<StructureSection load='4oy2' size='340' side='right'caption='[[4oy2]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4oy2]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OY2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OY2 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4oy2]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OY2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OY2 FirstGlance]. <br>
-
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
-
<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone_acetyltransferase Histone acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.48 2.3.1.48] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4oy2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oy2 OCA], [https://pdbe.org/4oy2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4oy2 RCSB], [https://www.ebi.ac.uk/pdbsum/4oy2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4oy2 ProSAT]</span></td></tr>
-
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4oy2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oy2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4oy2 RCSB], [http://www.ebi.ac.uk/pdbsum/4oy2 PDBsum]</span></td></tr>
+
</table>
-
<table>
+
== Function ==
 +
[https://www.uniprot.org/uniprot/TAF1_YEAST TAF1_YEAST] Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.<ref>PMID:8980232</ref> <ref>PMID:10788514</ref> <ref>PMID:12138208</ref> <ref>PMID:12516863</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 16: Line 18:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 4oy2" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Transcription initiation factors 3D structures|Transcription initiation factors 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Histone acetyltransferase]]
+
[[Category: Large Structures]]
-
[[Category: Bhattacharya, S.]]
+
[[Category: Saccharomyces cerevisiae S288C]]
-
[[Category: Jacobson, R H.]]
+
[[Category: Bhattacharya S]]
-
[[Category: Lou, X.]]
+
[[Category: Jacobson RH]]
-
[[Category: Rajashankar, K.]]
+
[[Category: Lou X]]
-
[[Category: Webb, P.]]
+
[[Category: Rajashankar K]]
-
[[Category: Rna pol ii initiation factor]]
+
[[Category: Webb P]]
-
[[Category: Taf1]]
+
-
[[Category: Taf7]]
+
-
[[Category: Tfiid]]
+
-
[[Category: Transcription]]
+

Current revision

Crystal structure of TAF1-TAF7, a TFIID subcomplex

PDB ID 4oy2

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4oy2"
Personal tools