4lq5

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==Crystal structure of ligand binding domain of CysB, a LysR member from Salmonella typhimurium LT2 in complex with effector ligand, O-acetylserine at 2.8A==
==Crystal structure of ligand binding domain of CysB, a LysR member from Salmonella typhimurium LT2 in complex with effector ligand, O-acetylserine at 2.8A==
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<StructureSection load='4lq5' size='340' side='right' caption='[[4lq5]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='4lq5' size='340' side='right'caption='[[4lq5]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4lq5]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LQ5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LQ5 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4lq5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LQ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LQ5 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OAS:O-ACETYLSERINE'>OAS</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.803&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4gwo|4gwo]], [[4gxa|4gxa]], [[4lon|4lon]], [[4lp2|4lp2]], [[4lq2|4lq2]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OAS:O-ACETYLSERINE'>OAS</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lq5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lq5 RCSB], [http://www.ebi.ac.uk/pdbsum/4lq5 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lq5 OCA], [https://pdbe.org/4lq5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lq5 RCSB], [https://www.ebi.ac.uk/pdbsum/4lq5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lq5 ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CYSB_SALTY CYSB_SALTY] This protein is a positive regulator of gene expression for the cysteine regulon, a system of 10 or more loci involved in the biosynthesis of L-cysteine from inorganic sulfate. The inducer for CysB is N-acetylserine. CysB inhibits its own transcription.
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==See Also==
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*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Kumaran, S.]]
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[[Category: Large Structures]]
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[[Category: Mittal, M.]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
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[[Category: Singh, A K.]]
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[[Category: Kumaran S]]
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[[Category: Cytoplasmic]]
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[[Category: Mittal M]]
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[[Category: Dna binding]]
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[[Category: Singh AK]]
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[[Category: Gene regulation]]
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[[Category: Lttr]]
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[[Category: N-acetyl serine binding]]
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[[Category: O-acetyl serine]]
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[[Category: Rossmann fold]]
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[[Category: Transcriptional regulation]]
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[[Category: Whth motif/ pbp type ii alpha/beta fold]]
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Current revision

Crystal structure of ligand binding domain of CysB, a LysR member from Salmonella typhimurium LT2 in complex with effector ligand, O-acetylserine at 2.8A

PDB ID 4lq5

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