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1cz2

From Proteopedia

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[[Image:1cz2.jpg|left|200px]]
 
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{{Structure
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==SOLUTION STRUCTURE OF WHEAT NS-LTP COMPLEXED WITH PROSTAGLANDIN B2.==
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|PDB= 1cz2 |SIZE=350|CAPTION= <scene name='initialview01'>1cz2</scene>
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<StructureSection load='1cz2' size='340' side='right'caption='[[1cz2]]' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=E2P:PROSTAGLANDIN B2'>E2P</scene>
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<table><tr><td colspan='2'>[[1cz2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Triticum_aestivum Triticum aestivum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CZ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CZ2 FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=E2P:PROSTAGLANDIN+B2'>E2P</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cz2 OCA], [https://pdbe.org/1cz2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cz2 RCSB], [https://www.ebi.ac.uk/pdbsum/1cz2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cz2 ProSAT]</span></td></tr>
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</table>
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'''SOLUTION STRUCTURE OF WHEAT NS-LTP COMPLEXED WITH PROSTAGLANDIN B2.'''
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== Function ==
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[https://www.uniprot.org/uniprot/NLTP1_WHEAT NLTP1_WHEAT] Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
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== Evolutionary Conservation ==
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==Overview==
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[[Image:Consurf_key_small.gif|200px|right]]
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The 3D solution structure of wheat nonspecific lipid transfer protein (ns-LTP) complexed with prostaglandin B2, a lipid with both vinyl and hydroxylated groups, has been determined by 1H 2D NMR. The global fold of the protein is close to the previously published structures of wheat, maize, barley and rice ns-LTPs. The ligand is almost completely embedded in the hydrophobic core of the protein. Structure comparisons of free and bound wheat ns-LTP reveal that the binding of prostaglandin B2 hardly affects the global fold of the protein. The structural data on this unusual complex are discussed and compared with other known ns-LTP lipid-complexes.
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cz/1cz2_consurf.spt"</scriptWhenChecked>
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1CZ2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Triticum_aestivum Triticum aestivum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CZ2 OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==Reference==
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</jmolCheckbox>
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The wide binding properties of a wheat nonspecific lipid transfer protein. Solution structure of a complex with prostaglandin B2., Tassin-Moindrot S, Caille A, Douliez JP, Marion D, Vovelle F, Eur J Biochem. 2000 Feb;267(4):1117-24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10672021 10672021]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1cz2 ConSurf].
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[[Category: Single protein]]
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Triticum aestivum]]
[[Category: Triticum aestivum]]
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[[Category: Caille, A.]]
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[[Category: Caille A]]
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[[Category: Douliez, J P.]]
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[[Category: Douliez J-P]]
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[[Category: Marion, D.]]
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[[Category: Marion D]]
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[[Category: Tassin-Moindrot, S.]]
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[[Category: Tassin-Moindrot S]]
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[[Category: Vovelle, F.]]
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[[Category: Vovelle F]]
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[[Category: E2P]]
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[[Category: protein complex alpha helix]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:30:38 2008''
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Current revision

SOLUTION STRUCTURE OF WHEAT NS-LTP COMPLEXED WITH PROSTAGLANDIN B2.

PDB ID 1cz2

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