1czg

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[[Image:1czg.gif|left|200px]]
 
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{{Structure
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==STRUCTURE OF THE G62T MUTANT OF SHIGA-LIKE TOXIN I B SUBUNIT==
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|PDB= 1czg |SIZE=350|CAPTION= <scene name='initialview01'>1czg</scene>, resolution 2.50&Aring;
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<StructureSection load='1czg' size='340' side='right'caption='[[1czg]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[1czg]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Phage_h30 Phage h30]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CZG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CZG FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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|GENE=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1czg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1czg OCA], [https://pdbe.org/1czg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1czg RCSB], [https://www.ebi.ac.uk/pdbsum/1czg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1czg ProSAT]</span></td></tr>
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}}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/STXB_BPH19 STXB_BPH19] The B subunit is responsible for the binding of the holotoxin to specific receptors on the target cell surface, such as globotriaosylceramide (Gb3) in human intestinal microvilli.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cz/1czg_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1czg ConSurf].
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<div style="clear:both"></div>
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'''STRUCTURE OF THE G62T MUTANT OF SHIGA-LIKE TOXIN I B SUBUNIT'''
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==See Also==
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*[[Shiga toxin 3D structures|Shiga toxin 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1CZG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_pyogenes_phage_h4489a Streptococcus pyogenes phage h4489a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CZG OCA].
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Phage h30]]
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[[Category: Streptococcus pyogenes phage h4489a]]
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[[Category: Bast D]]
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[[Category: Bast, D.]]
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[[Category: Brunton JL]]
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[[Category: Brunton, J L.]]
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[[Category: Ling H]]
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[[Category: Ling, H.]]
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[[Category: Read RJ]]
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[[Category: Read, R J.]]
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[[Category: bacterial toxin]]
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[[Category: ob-fold]]
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[[Category: protein-carbohydrate recognition]]
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[[Category: sugar receptor binding domain]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:30:47 2008''
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Current revision

STRUCTURE OF THE G62T MUTANT OF SHIGA-LIKE TOXIN I B SUBUNIT

PDB ID 1czg

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