1d59

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[[Image:1d59.gif|left|200px]]
 
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{{Structure
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==CRYSTAL STRUCTURE OF 4-STRANDED OXYTRICHA TELOMERIC DNA==
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|PDB= 1d59 |SIZE=350|CAPTION= <scene name='initialview01'>1d59</scene>, resolution 2.300&Aring;
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<StructureSection load='1d59' size='340' side='right'caption='[[1d59]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[1d59]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D59 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1D59 FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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|GENE=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1d59 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d59 OCA], [https://pdbe.org/1d59 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1d59 RCSB], [https://www.ebi.ac.uk/pdbsum/1d59 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1d59 ProSAT]</span></td></tr>
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}}
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</table>
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__TOC__
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'''CRYSTAL STRUCTURE OF 4-STRANDED OXYTRICHA TELOMERIC DNA'''
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Kang C]]
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==Overview==
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[[Category: Moyzis R]]
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The sequence d(GGGGTTTTGGGG) from the 3' overhang of the Oxytricha telomere has been crystallized and its three-dimensional structure solved to 2.5 A resolution. The oligonucleotide forms hairpins, two of which join to make a four-stranded helical structure with the loops containing four thymine residues at either end. The guanine residues are held together by cyclic hydrogen bonding and an ion is located in the centre. The four guanine residues in each segment have a glycosyl conformation that alternates between anti and syn. There are two four-stranded molecules in the asymmetric unit showing that the structure has some intrinsic flexibility.
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[[Category: Ratliff R]]
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[[Category: Rich A]]
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==About this Structure==
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[[Category: Zhang X]]
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1D59 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D59 OCA].
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==Reference==
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Crystal structure of four-stranded Oxytricha telomeric DNA., Kang C, Zhang X, Ratliff R, Moyzis R, Rich A, Nature. 1992 Mar 12;356(6365):126-31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1545863 1545863]
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[[Category: Protein complex]]
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[[Category: Kang, C.]]
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[[Category: Moyzis, R.]]
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[[Category: Ratliff, R.]]
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[[Category: Rich, A.]]
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[[Category: Zhang, X.]]
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[[Category: loop]]
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[[Category: quadruple helix]]
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[[Category: tetraplex]]
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[[Category: u-dna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:33:03 2008''
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Current revision

CRYSTAL STRUCTURE OF 4-STRANDED OXYTRICHA TELOMERIC DNA

PDB ID 1d59

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