4u4m
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of 0.5M urea unfolded YagE, a KDG aldolase protein in complex with Pyruvate== | |
| - | + | <StructureSection load='4u4m' size='340' side='right'caption='[[4u4m]], [[Resolution|resolution]] 3.09Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4u4m]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U4M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4U4M FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.09Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene>, <scene name='pdbligand=URE:UREA'>URE</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4u4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u4m OCA], [https://pdbe.org/4u4m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4u4m RCSB], [https://www.ebi.ac.uk/pdbsum/4u4m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4u4m ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/YAGE_ECOLI YAGE_ECOLI] Catalyzes the formation of 2-keto-3-deoxy-galactonate (KDGal) from pyruvate and glyceraldehyde. Overexpression leads to increased growth (over 2 hours) in the presence of the antibiotics norfloxacin, ampicillin and streptomycin. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli K-12]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bhaskar V]] | ||
| + | [[Category: Krishnaswamy S]] | ||
| + | [[Category: Manicka S]] | ||
| + | [[Category: Manoj Kumar P]] | ||
Current revision
Crystal structure of 0.5M urea unfolded YagE, a KDG aldolase protein in complex with Pyruvate
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