4ua1

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'''Unreleased structure'''
 
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The entry 4ua1 is ON HOLD
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==Crystal structure of dual function transcriptional regulator MerR form Bacillus megaterium MB1 in complex with mercury (II) ion==
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<StructureSection load='4ua1' size='340' side='right'caption='[[4ua1]], [[Resolution|resolution]] 2.56&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4ua1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Priestia_megaterium Priestia megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UA1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UA1 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.56&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ua1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ua1 OCA], [https://pdbe.org/4ua1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ua1 RCSB], [https://www.ebi.ac.uk/pdbsum/4ua1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ua1 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q799U3_PRIMG Q799U3_PRIMG] Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site.[ARBA:ARBA00024874]
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Authors: Chang, C.C., Lin, L.Y., Zou, X.W., Huang, C.C., Chan, N.L.
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==See Also==
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*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
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Description: Crystal structure of dual function transcriptional regulator MerR form Bacillus megaterium MB1 in complex with mercury (II) ion
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Priestia megaterium]]
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[[Category: Chan NL]]
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[[Category: Chang CC]]
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[[Category: Huang CC]]
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[[Category: Lin LY]]
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[[Category: Zou XW]]

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Crystal structure of dual function transcriptional regulator MerR form Bacillus megaterium MB1 in complex with mercury (II) ion

PDB ID 4ua1

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