4uvg
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4uvg is ON HOLD Authors: Read, J.A., Gingell, H., Madhavapeddi, P., Ghorpade, S., Cowan, S. Description: Discovery of pyrimidine isoxazoles InhA in...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Discovery of pyrimidine isoxazoles InhA in complex with compound 15== | |
| + | <StructureSection load='4uvg' size='340' side='right'caption='[[4uvg]], [[Resolution|resolution]] 1.92Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4uvg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UVG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UVG FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.92Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=A0C:5-[(4,6-DIMETHYLPYRIMIDIN-2-YL)SULFANYLMETHYL]ISOXAZOLE-3-CARBOXAMIDE'>A0C</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uvg OCA], [https://pdbe.org/4uvg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uvg RCSB], [https://www.ebi.ac.uk/pdbsum/4uvg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uvg ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/INHA_MYCTU INHA_MYCTU] | ||
| - | + | ==See Also== | |
| - | + | *[[Enoyl-Acyl-Carrier Protein Reductase 3D structures|Enoyl-Acyl-Carrier Protein Reductase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
| + | [[Category: Cowan S]] | ||
| + | [[Category: Ghorpade S]] | ||
| + | [[Category: Gingell H]] | ||
| + | [[Category: Madhavapeddi P]] | ||
| + | [[Category: Read JA]] | ||
Current revision
Discovery of pyrimidine isoxazoles InhA in complex with compound 15
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