This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4mal

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:06, 21 December 2022) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
-
==TPR2 of FimV from P. aeruginosa (PAO1)==
+
 
-
<StructureSection load='4mal' size='340' side='right' caption='[[4mal]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
+
==TPR3 of FimV from P. aeruginosa (PAO1)==
 +
<StructureSection load='4mal' size='340' side='right'caption='[[4mal]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4mal]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MAL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MAL FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4mal]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MAL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MAL FirstGlance]. <br>
-
</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mal OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mal RCSB], [http://www.ebi.ac.uk/pdbsum/4mal PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mal OCA], [https://pdbe.org/4mal PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mal RCSB], [https://www.ebi.ac.uk/pdbsum/4mal PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mal ProSAT]</span></td></tr>
-
<table>
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/FIMV_PSEAE FIMV_PSEAE] Inner membrane hub protein that plays both cAMP-dependent and cAMP-independent roles in twitching motility (PubMed:27297880, PubMed:28583947). Regulates intracellular cyclic AMP (cAMP) levels through the activation of adenylate cyclase CyaB (PubMed:20345659). Plays an essential role in a number of virulence mechanisms including type IV pilus (T4P)-mediated assembly and twitching motility as well as cAMP-dependent virulence gene expression (PubMed:21097635, PubMed:10846211). Mediates also type II secretion (T2S) of lipases and proteases (PubMed:21527471). In addition, mediates the cAMP-independent localization of multiple T4P structural and regulatory components to the cell poles (PubMed:21527471, PubMed:27297880, PubMed:28583947). This role in directing proteins to the cell pole is not restricted to type IV component and involves other proteins such as the diguanylate cyclase DgcP (By similarity).[UniProtKB:A0A0H2ZC68]<ref>PMID:10846211</ref> <ref>PMID:20345659</ref> <ref>PMID:21097635</ref> <ref>PMID:21527471</ref> <ref>PMID:27297880</ref> <ref>PMID:28583947</ref>
 +
== References ==
 +
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Burrows, L L.]]
+
[[Category: Large Structures]]
-
[[Category: Daniel-Ivad, M.]]
+
[[Category: Pseudomonas aeruginosa PAO1]]
-
[[Category: Howell, P L.]]
+
[[Category: Burrows LL]]
-
[[Category: Junop, M S.]]
+
[[Category: Daniel-Ivad M]]
-
[[Category: Nguyen, Y.]]
+
[[Category: Howell PL]]
-
[[Category: Sugiman-Marangos, S N.]]
+
[[Category: Junop MS]]
-
[[Category: Zhang, K.]]
+
[[Category: Nguyen Y]]
-
[[Category: Tpr]]
+
[[Category: Sugiman-Marangos SN]]
-
[[Category: Unknown function]]
+
[[Category: Zhang K]]

Current revision

TPR3 of FimV from P. aeruginosa (PAO1)

PDB ID 4mal

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4mal"
Personal tools