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4qb8

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==Crystal Structure of beta-lactamase from M.tuberculosis forming Michaelis Menten with Tebipenem==
==Crystal Structure of beta-lactamase from M.tuberculosis forming Michaelis Menten with Tebipenem==
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<StructureSection load='4qb8' size='340' side='right' caption='[[4qb8]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
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<StructureSection load='4qb8' size='340' side='right'caption='[[4qb8]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4qb8]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QB8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QB8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4qb8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QB8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QB8 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1TE:TEBIPENEM'>1TE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.758&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4q8i|4q8i]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1TE:TEBIPENEM'>1TE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qb8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qb8 OCA], [https://pdbe.org/4qb8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qb8 RCSB], [https://www.ebi.ac.uk/pdbsum/4qb8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qb8 ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qb8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qb8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qb8 RCSB], [http://www.ebi.ac.uk/pdbsum/4qb8 PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/BLAC_MYCTU BLAC_MYCTU]
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==See Also==
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*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Beta-lactamase]]
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[[Category: Large Structures]]
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[[Category: Blanchard, J.]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Hazra, S.]]
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[[Category: Blanchard J]]
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[[Category: 3-layer sandwich]]
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[[Category: Hazra S]]
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[[Category: Carbapenem]]
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[[Category: Dd-peptidase/beta-lactamase superfamily]]
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[[Category: Destroying betalactam antibiotic]]
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[[Category: Hydrolase-antibiotic complex]]
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[[Category: Tebipenem pivoxil]]
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Current revision

Crystal Structure of beta-lactamase from M.tuberculosis forming Michaelis Menten with Tebipenem

PDB ID 4qb8

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