4r3q
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4r3q is ON HOLD Authors: Lu, J, Feng, J, Zhou, W, Yang, X, Shen, Y Description: Crystal structure of SYCE3) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of SYCE3== | |
| - | + | <StructureSection load='4r3q' size='340' side='right'caption='[[4r3q]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4r3q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R3Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4R3Q FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.901Å</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4r3q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r3q OCA], [https://pdbe.org/4r3q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4r3q RCSB], [https://www.ebi.ac.uk/pdbsum/4r3q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4r3q ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SYCE3_MOUSE SYCE3_MOUSE] Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for chromosome loading of the central element-specific SCS proteins, and for initiating synapsis between homologous chromosomes. Chromosome loading appears to require SYCP1. Required for fertility. May play a role in apoptosis of spermatogenic cells and pathogenesis of cryptorchidism.<ref>PMID:20407872</ref> <ref>PMID:21637789</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Feng J]] | ||
| + | [[Category: Lu J]] | ||
| + | [[Category: Shen Y]] | ||
| + | [[Category: Yang X]] | ||
| + | [[Category: Zhou W]] | ||
Current revision
Crystal structure of SYCE3
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Categories: Large Structures | Mus musculus | Feng J | Lu J | Shen Y | Yang X | Zhou W
