4r4y
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structural basis of a point mutation that causes the genetic disease Aspartylglucosaminuria== | |
| + | <StructureSection load='4r4y' size='340' side='right'caption='[[4r4y]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4r4y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Elizabethkingia_miricola Elizabethkingia miricola]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R4Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4R4Y FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SD4:N-HYDROXY-L-ASPARAGINE'>SD4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4r4y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r4y OCA], [https://pdbe.org/4r4y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4r4y RCSB], [https://www.ebi.ac.uk/pdbsum/4r4y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4r4y ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ASPG_ELIMR ASPG_ELIMR] Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins. Requires that the glycosylated asparagine moiety is not substituted on its N-(R1) and C- (R2) terminus. | ||
| - | + | ==See Also== | |
| - | + | *[[Asparaginase 3D structures|Asparaginase 3D structures]] | |
| - | + | *[[Glycosylasparaginase|Glycosylasparaginase]] | |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Elizabethkingia miricola]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Damodharan L]] | ||
| + | [[Category: Guo HC]] | ||
| + | [[Category: Pande S]] | ||
| + | [[Category: Sui L]] | ||
Current revision
Structural basis of a point mutation that causes the genetic disease Aspartylglucosaminuria
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