4r5i
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4r5i is ON HOLD Authors: Leu, J.I., Zhang, P., Murphy, M.E., Marmorstein, R., George, D.L. Description: Crystal structure of the DnaK C-terminus wi...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the DnaK C-terminus with the substrate peptide NRLLLTG== | |
| + | <StructureSection load='4r5i' size='340' side='right'caption='[[4r5i]], [[Resolution|resolution]] 1.97Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4r5i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R5I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4R5I FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9702Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4r5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r5i OCA], [https://pdbe.org/4r5i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4r5i RCSB], [https://www.ebi.ac.uk/pdbsum/4r5i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4r5i ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DNAK_ECOLI DNAK_ECOLI] Plays an essential role in the initiation of phage lambda DNA replication, where it acts in an ATP-dependent fashion with the DnaJ protein to release lambda O and P proteins from the preprimosomal complex. DnaK is also involved in chromosomal DNA replication, possibly through an analogous interaction with the DnaA protein. Also participates actively in the response to hyperosmotic shock.[HAMAP-Rule:MF_00332] | ||
| - | + | ==See Also== | |
| - | + | *[[Heat Shock Protein structures|Heat Shock Protein structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli K-12]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Synthetic construct]] | ||
| + | [[Category: George DL]] | ||
| + | [[Category: Leu JI]] | ||
| + | [[Category: Marmorstein R]] | ||
| + | [[Category: Murphy ME]] | ||
| + | [[Category: Zhang P]] | ||
Current revision
Crystal structure of the DnaK C-terminus with the substrate peptide NRLLLTG
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