4c18

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==The structure of the Tsi2 dimer with a disulfide bond==
==The structure of the Tsi2 dimer with a disulfide bond==
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<StructureSection load='4c18' size='340' side='right' caption='[[4c18]], [[Resolution|resolution]] 1.49&Aring;' scene=''>
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<StructureSection load='4c18' size='340' side='right'caption='[[4c18]], [[Resolution|resolution]] 1.49&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4c18]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C18 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4C18 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4c18]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C18 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4C18 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4c15|4c15]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.49&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c18 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c18 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4c18 RCSB], [http://www.ebi.ac.uk/pdbsum/4c18 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4c18 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c18 OCA], [https://pdbe.org/4c18 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4c18 RCSB], [https://www.ebi.ac.uk/pdbsum/4c18 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4c18 ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TSI2_PSEAE TSI2_PSEAE] Immunity protein that plays a role in preventing early activation of toxin Tse2. Binds to a large surface of Tse2 and thereby occludes the active site to specifically inhibits Tse2.<ref>PMID:22310046</ref> <ref>PMID:22511866</ref> <ref>PMID:26749446</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Boraston, A B.]]
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[[Category: Large Structures]]
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[[Category: Nano, F E.]]
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[[Category: Pseudomonas aeruginosa]]
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[[Category: Robb, C S.]]
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[[Category: Boraston AB]]
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[[Category: Anti-toxin]]
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[[Category: Nano FE]]
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[[Category: Immunity protein]]
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[[Category: Robb CS]]
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[[Category: T6ss]]
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[[Category: Toxin]]
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Current revision

The structure of the Tsi2 dimer with a disulfide bond

PDB ID 4c18

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