2mtg
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Solution structure of the RRM1 of human LARP6== | |
| - | + | <StructureSection load='2mtg' size='340' side='right'caption='[[2mtg]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2mtg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MTG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MTG FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mtg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mtg OCA], [https://pdbe.org/2mtg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mtg RCSB], [https://www.ebi.ac.uk/pdbsum/2mtg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mtg ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/LARP6_HUMAN LARP6_HUMAN] Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5' UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9.<ref>PMID:20603131</ref> <ref>PMID:21746880</ref> <ref>PMID:22190748</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Atkinson AR]] | ||
| + | [[Category: Conte MR]] | ||
| + | [[Category: Kelly G]] | ||
| + | [[Category: Martino L]] | ||
Current revision
Solution structure of the RRM1 of human LARP6
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