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1e82

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[[Image:1e82.gif|left|200px]]
 
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{{Structure
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==Endothiapepsin complex with renin inhibitor MERCK-KGAA-EMD59601==
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|PDB= 1e82 |SIZE=350|CAPTION= <scene name='initialview01'>1e82</scene>, resolution 2.05&Aring;
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<StructureSection load='1e82' size='340' side='right'caption='[[1e82]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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|SITE= <scene name='pdbsite=CAT:ASP+Dyad+Catalytic+Site+Plus+An+Associated+Solvent+Peak'>CAT</scene>
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MRM:4-AMINOPIPERIDINE-1-CARBOXYLIC ACID'>MRM</scene>
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<table><tr><td colspan='2'>[[1e82]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E82 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E82 FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Mucorpepsin Mucorpepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.23 3.4.23.23]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=M90:(2S)-1-{[(2R)-1-{[(2S,3R)-1-CYCLOHEXYL-3-HYDROXY-4-(PYRIDIN-4-YLOXY)BUTAN-2-YL]AMINO}-3-(METHYLSULFANYL)-1-OXOPROPAN-2-YL]AMINO}-1-OXO-3-PHENYLPROPAN-2-YL+4-AMINOPIPERIDINE-1-CARBOXYLATE'>M90</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e82 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e82 OCA], [https://pdbe.org/1e82 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e82 RCSB], [https://www.ebi.ac.uk/pdbsum/1e82 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e82 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CARP_CRYPA CARP_CRYPA]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e8/1e82_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1e82 ConSurf].
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<div style="clear:both"></div>
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'''ENDOTHIAPEPSIN COMPLEX WITH RENIN INHIBITOR MERCK-KGAA-EMD59601'''
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==See Also==
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*[[Pepsin|Pepsin]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1E82 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E82 OCA].
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[[Category: Cryphonectria parasitica]]
[[Category: Cryphonectria parasitica]]
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[[Category: Mucorpepsin]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Cooper JB]]
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[[Category: Cooper, J B.]]
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[[Category: Raddatz P]]
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[[Category: Raddatz, P.]]
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[[Category: Read JA]]
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[[Category: Read, J A.]]
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[[Category: Rippmann F]]
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[[Category: Rippmann, F.]]
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[[Category: Toldo L]]
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[[Category: Toldo, L.]]
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[[Category: MRM]]
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[[Category: hydrolase (acid proteinase)]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:51:26 2008''
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Current revision

Endothiapepsin complex with renin inhibitor MERCK-KGAA-EMD59601

PDB ID 1e82

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