4tr6

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==Crystal structure of DNA polymerase sliding clamp from Bacillus subtilis==
==Crystal structure of DNA polymerase sliding clamp from Bacillus subtilis==
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<StructureSection load='4tr6' size='340' side='right' caption='[[4tr6]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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<StructureSection load='4tr6' size='340' side='right'caption='[[4tr6]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4tr6]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TR6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TR6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4tr6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TR6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TR6 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tr6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tr6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4tr6 RCSB], [http://www.ebi.ac.uk/pdbsum/4tr6 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4tr6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tr6 OCA], [https://pdbe.org/4tr6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4tr6 RCSB], [https://www.ebi.ac.uk/pdbsum/4tr6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4tr6 ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DPO3B_BACSU DPO3B_BACSU] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4tr6" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: DNA-directed DNA polymerase]]
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[[Category: Bacillus subtilis subsp. subtilis str. 168]]
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[[Category: Burnouf, D.]]
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[[Category: Large Structures]]
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[[Category: Ennifar, E.]]
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[[Category: Burnouf D]]
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[[Category: Olieric, V.]]
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[[Category: Ennifar E]]
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[[Category: Wolff, P.]]
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[[Category: Olieric V]]
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[[Category: Dna binding protein]]
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[[Category: Wolff P]]
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[[Category: Dna polymerase]]
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[[Category: Processivity]]
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[[Category: Sliding clamp]]
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Current revision

Crystal structure of DNA polymerase sliding clamp from Bacillus subtilis

PDB ID 4tr6

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