This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4pis
From Proteopedia
(Difference between revisions)
| (4 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| + | |||
==Crystal structure of human adenovirus 8 protease in complex with a nitrile inhibitor== | ==Crystal structure of human adenovirus 8 protease in complex with a nitrile inhibitor== | ||
| - | <StructureSection load='4pis' size='340' side='right' caption='[[4pis]], [[Resolution|resolution]] 2.10Å' scene=''> | + | <StructureSection load='4pis' size='340' side='right'caption='[[4pis]], [[Resolution|resolution]] 2.10Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4pis]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PIS OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4pis]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_adenovirus_D8 Human adenovirus D8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PIS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PIS FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3FU:N~2~-[(2R)-2-(3,5-DICHLOROPHENYL)-2-(DIMETHYLAMINO)ACETYL]-N-({2-[(Z)-IMINOMETHYL]PYRIMIDIN-4-YL}METHYL)-L-ISOLEUCINAMIDE'>3FU</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3FU:N~2~-[(2R)-2-(3,5-DICHLOROPHENYL)-2-(DIMETHYLAMINO)ACETYL]-N-({2-[(Z)-IMINOMETHYL]PYRIMIDIN-4-YL}METHYL)-L-ISOLEUCINAMIDE'>3FU</scene></td></tr> | |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pis OCA], [https://pdbe.org/4pis PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pis RCSB], [https://www.ebi.ac.uk/pdbsum/4pis PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pis ProSAT]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/B9A5C1_ADE08 B9A5C1_ADE08] | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 15: | Line 18: | ||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4pis" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Altmann | + | [[Category: Human adenovirus D8]] |
| - | [[Category: Bernardi | + | [[Category: Large Structures]] |
| - | [[Category: Combrink | + | [[Category: Altmann E]] |
| - | [[Category: Ellis | + | [[Category: Bernardi A]] |
| - | [[Category: Erbel | + | [[Category: Combrink K]] |
| - | [[Category: Grosche | + | [[Category: Ellis D]] |
| - | [[Category: Hughes | + | [[Category: Erbel P]] |
| - | [[Category: Jarousse | + | [[Category: Grosche P]] |
| - | + | [[Category: Hughes N]] | |
| - | + | [[Category: Jarousse N]] | |
| - | + | [[Category: Mac Sweeney A]] | |
| - | [[Category: Sweeney | + | [[Category: Melkko S]] |
| - | [[Category: | + | [[Category: Ramage P]] |
| - | [[Category: | + | [[Category: Sirockin F]] |
| - | [[Category: | + | |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal structure of human adenovirus 8 protease in complex with a nitrile inhibitor
| |||||||||||
Categories: Human adenovirus D8 | Large Structures | Altmann E | Bernardi A | Combrink K | Ellis D | Erbel P | Grosche P | Hughes N | Jarousse N | Mac Sweeney A | Melkko S | Ramage P | Sirockin F
